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T P Conrads

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Articles 10
Citations 351
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Recent Articles
1.
Teng P, Wang G, Hood B, Conrads K, Hamilton C, Maxwell G, et al.
Br J Cancer . 2013 Nov; 110(1):123-32. PMID: 24178762
Background: The majority of patients diagnosed with advanced epithelial ovarian carcinoma (EOC) relapse with resistant disease, and there are no biomarkers that possess clinical utility to identify or monitor these...
2.
Brouwers F, Petricoin 3rd E, Ksinantova L, Breza J, Rajapakse V, Ross S, et al.
Endocr Relat Cancer . 2005 Jun; 12(2):263-72. PMID: 15947101
Metastatic lesions occur in up to 36% of patients with pheochromocytoma. Currently there is no way to reliably detect or predict which patients are at risk for metastatic pheochromocytoma. Thus,...
3.
Conrads T, Fusaro V, Ross S, Johann D, Rajapakse V, Hitt B, et al.
Endocr Relat Cancer . 2004 May; 11(2):163-78. PMID: 15163296
Serum proteomic pattern diagnostics is an emerging paradigm employing low-resolution mass spectrometry (MS) to generate a set of biomarker classifiers. In the present study, we utilized a well-controlled ovarian cancer...
4.
Li L, Masselon C, Anderson G, Pasa-Tolic L, Lee S, Shen Y, et al.
Anal Chem . 2001 Jul; 73(14):3312-22. PMID: 11476231
Tandem mass spectrometry (MS/MS) plays an important role in the unambiguous identification and structural elucidation of biomolecules. In contrast to conventional MS/MS approaches for protein identification where an individual polypeptide...
5.
Smith R, Pasa-Tolic L, Lipton M, Jensen P, Anderson G, Shen Y, et al.
Electrophoresis . 2001 Jun; 22(9):1652-68. PMID: 11425221
The patterns of gene expression, post-translational modifications, protein/biomolecular interactions, and how these may be affected by changes in the environment, cannot be accurately predicted from DNA sequences. Approaches for proteome...
6.
Goshe M, Conrads T, Panisko E, Angell N, Veenstra T, Smith R
Anal Chem . 2001 Jun; 73(11):2578-86. PMID: 11403303
A method has been developed that utilizes phosphoprotein isotope-coded affinity tags (PhIAT) that combines stable isotope and biotin labeling to enrich and quantitatively measure differences in the O-phosphorylation states of...
7.
Conrads T, Alving K, Veenstra T, Belov M, Anderson G, Anderson D, et al.
Anal Chem . 2001 May; 73(9):2132-9. PMID: 11354501
We describe the combined use of 15N-metabolic labeling and a cysteine-reactive biotin affinity tag to isolate and quantitate cysteine-containing polypeptides (Cys-polypeptides) from Deinococcus radiodurans as well as from mouse B16...
8.
Shen Y, Zhao R, Belov M, Conrads T, Anderson G, Tang K, et al.
Anal Chem . 2001 May; 73(8):1766-75. PMID: 11338590
In this study, high-efficiency packed capillary reversed-phase liquid chromatography (RPLC) coupled on-line with high-performance Fourier transform ion cyclotron resonance (FTICR) mass spectrometry has been investigated for the characterization of complex...
9.
Belov M, Nikolaev E, Anderson G, Udseth H, Conrads T, Veenstra T, et al.
Anal Chem . 2001 Feb; 73(2):253-61. PMID: 11199974
The coupling of Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) with electrospray ionization has advanced the analysis of large biopolymers and provided the basis for high-throughput protein characterization...
10.
Conrads T, Anderson G, Veenstra T, Pasa-Tolic L, Smith R
Anal Chem . 2000 Aug; 72(14):3349-54. PMID: 10939410
An enabling capability for proteomics would be the ability to study protein expression on a global scale. While several different separation and analysis options are being investigated to advance the...