T P Brien
Overview
Explore the profile of T P Brien including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
259
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0
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Recent Articles
1.
Karuman P, Gozani O, Odze R, Zhou X, Zhu H, Shaw R, et al.
Mol Cell
. 2001 Jun;
7(6):1307-19.
PMID: 11430832
Here, we investigate the mechanism and function of LKB1, a Ser/Thr kinase mutated in Peutz-Jegher syndrome (PJS). We demonstrate that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis...
2.
Brien T, Farraye F, Odze R
Mod Pathol
. 2001 May;
14(5):389-96.
PMID: 11353047
Preoperative chemotherapy combined with radiotherapy (chemrad) is a common type of neoadjuvant treatment for esophageal adenocarcinoma or squamous cell carcinoma. The purpose of this study was to describe the clinical,...
3.
Depowski P, Rosenthal S, Brien T, Stylos S, Johnson R, Ross J
Mod Pathol
. 2000 May;
13(5):542-7.
PMID: 10824926
Topoisomerase IIalpha (topo IIalpha) plays a key role in DNA replication and is a target for multiple chemotherapeutic agents. In breast cancer, topo II expression has been linked to cell...
4.
Brien T, Odze R, Sheehan C, McKenna B, Ross J
Hum Pathol
. 2000 Feb;
31(1):35-9.
PMID: 10665910
The HER-2/neu oncogene is localized to chromosome 17q and shares significant homology with the epidermal growth factor receptor. HER-2/neu protein overexpression has been associated with poor prognosis in a variety...
5.
Depowski P, Brien T, Sheehan C, Stylos S, Johnson R, Ross J
Am J Clin Pathol
. 1999 Oct;
112(4):459-69.
PMID: 10510669
The HER-2/neu oncogene, localized to chromosome 17q, shares substantial homology with the epidermal growth factor receptor. HER-2/neu gene amplification and protein overexpression have been associated with poor prognosis in breast...
6.
PHELPS K, Naylor K, Brien T, Wilbur H, Haqqie S
Am J Med Sci
. 1999 Sep;
318(3):181-5.
PMID: 10487408
A 70-year-old man with advanced obstructive nephropathy began to hemorrhage from the bladder after decompression with a Foley catheter. Manifestations of encephalopathy appeared after continuous irrigation with 1% alum for...
7.
Mu X, Brien T, Ross J, Lowry C, McKenna B
Cancer
. 1999 May;
87(2):93-9.
PMID: 10227600
Background: Telomerase is a ribonucleoprotein that maintains telomeric base pair repeats at the ends of mammalian chromosomes during DNA replication. Telomerase is expressed in various human tumors, some normal tissues,...
8.
Brien T, Depowski P, Sheehan C, Ross J, McKenna B
Mod Pathol
. 1998 Oct;
11(9):870-7.
PMID: 9758367
Molecular assays related to cell proliferation correlate with stage and/or survival in a variety of tumors. We immunostained formalin-fixed, paraffin-embedded tissue sections from 61 patients with gastric adenocarcinoma (21 biopsy...
9.
Brien T, Reddy P, Vincent P, Lewis E, Ross J, Saba T
Am J Physiol
. 1998 Apr;
274(3):L432-43.
PMID: 9530180
Plasma fibronectin (Fn) can both enhance phagocytic clearance of microparticulate debris by macrophages as well as incorporate it into the lung extracellular matrix (ECM). The goal of this study was...
10.
Kallakury B, Brien T, Lowry C, Muraca P, Fisher H, Kaufman Jr R, et al.
Diagn Mol Pathol
. 1997 Aug;
6(4):192-8.
PMID: 9360840
Telomerase adds a hexanucleotide telomeric sequence to the chromosomal ends during replication and is postulated to play a role in cellular senescence and immortalization. Thirty-four human prostate tissues (18 malignant;...