T P Akerboom
Overview
Explore the profile of T P Akerboom including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
663
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Recent Articles
1.
Ji Y, Akerboom T, Sies H, Thomas J
Methods Enzymol
. 1999 Jan;
301:145-51.
PMID: 9919562
No abstract available.
2.
Ji Y, Akerboom T, Sies H, Thomas J
Arch Biochem Biophys
. 1999 Jan;
362(1):67-78.
PMID: 9917330
The modification of reactive protein sulfhydryls by S-nitrosoglutathione and other NO donors has been studied by gel isoelectric focusing. S-nitrosylated, unmodified, and S-glutathiolated protein forms are differentiated by this method....
3.
Josch C, Sies H, Akerboom T
Biochem Pharmacol
. 1998 Sep;
56(6):763-71.
PMID: 9751082
The role of cysteinylglycine S-conjugate dipeptidases in the intrahepatic mercapturic acid pathway was investigated in rat liver. Subcellular compartmentation studies and liver perfusions were performed using monochlorobimane and bimane S-conjugates...
4.
Sies H, Dafre A, Ji Y, Akerboom T
Chem Biol Interact
. 1998 Jul;
111-112:177-85.
PMID: 9679553
Membrane-bound GST transferase (GSTm) occurs in hepatic microsomal and plasma membranes as well as in the outer mitochondrial membrane, and it is known to be activated by N-ethylmaleimide. We recently...
5.
Akerboom T, Ji Y, Wagner G, Sies H
Biochem Pharmacol
. 1997 Jan;
53(1):117-20.
PMID: 8960071
Glutathione transferase (GST)-catalysed S-nitrosoglutathione (GSNO) formation from alkyl nitrites was determined with the homodimers 1-1, 2-2, 3-3, and 4-4 isolated from rat liver. The 4-4 isoform showed a high specificity...
6.
Ji Y, Akerboom T, Sies H
Biochem J
. 1996 Jan;
313 ( Pt 2):377-80.
PMID: 8573068
The formation of S-nitrosoglutathione (GSNO) from amyl nitrite and n-butyl nitrite was studied in rat liver microsomes, employing N-ethylmaleimide (MalNEt) as an activator and indomethacin as an inhibitor of microsomal...
7.
Akerboom T, Sies H, Ziegler D
Arch Biochem Biophys
. 1995 Jan;
316(1):220-6.
PMID: 7840620
The oxidation of 2-(methylseleno)benzanilide and 2-selenylbenzanilide, metabolites of the antioxidant drug ebselen, was examined in reactions catalyzed by rat, pig, and guinea pig liver microsomes and in perfused rat liver....
8.
Wagner G, Schuch G, Akerboom T, Sies H
Biochem Pharmacol
. 1994 Sep;
48(6):1137-44.
PMID: 7945407
In vivo transport in plasma and in vitro transfer of ebselen to binding sites in the hepatocyte were studied. More than 90% of intravenously administered ebselen in mouse plasma is...
9.
Horbach M, Sies H, Akerboom T
Eur J Biochem
. 1994 May;
222(1):91-6.
PMID: 8200358
Glutathione transferases purified from plasma membrane and microsomal fractions from rat liver share similar enzymic properties. The activity of both proteins with 1-chloro-2,4-dinitrobenzene can be stimulated about 10-15-fold by N-ethylmaleimide....
10.