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T M Brushart

Explore the profile of T M Brushart including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1309
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Recent Articles
1.
Abdullah M, ODaly A, Vyas A, Rohde C, Brushart T
Exp Neurol . 2013 Aug; 249:1-7. PMID: 23933577
Preferential motor reinnervation (PMR) is the tendency for motor axons regenerating after repair of mixed nerve to reinnervate muscle nerve and/or muscle rather than cutaneous nerve or skin. PMR may...
2.
Brushart T, Aspalter M, Griffin J, Redett R, Hameed H, Zhou C, et al.
Exp Neurol . 2013 May; 247:272-81. PMID: 23707299
Myelinating Schwann cells express distinct sensory and motor phenotypes as defined by their differing patterns of growth factor production (Hoke et al., 2006). The heterogeneous growth factor requirements of sensory...
3.
Brushart T
Restor Neurol Neurosci . 2011 May; 1(3):281-7. PMID: 21551568
Previous experiments have shown that motor axons regenerating in mixed nerve will preferentially reinnervate a distal motor branch. The present experiments examine the mechanism through which this sensory-motor specificity is...
4.
Gordon T, Brushart T, Chan K
Neurol Res . 2008 Dec; 30(10):1012-22. PMID: 19079975
Objective: Poor functional recovery after peripheral nerve injury is generally attributed to irreversible target atrophy. In rats, we addressed the functional outcomes of prolonged neuronal separation from targets (chronic axotomy...
5.
Gordon T, Brushart T, Amirjani N, Chan K
Acta Neurochir Suppl . 2007 Nov; 100:3-11. PMID: 17985535
The declining capacity for injured peripheral nerves to regenerate their axons with time and distance is accounted for, at least in part, by the chronic axotomy of the neurons and...
6.
Hoke A, Redett R, Hameed H, Jari R, Zhou C, Li Z, et al.
J Neurosci . 2006 Sep; 26(38):9646-55. PMID: 16988035
Schwann cell phenotype is classified as either myelinating or nonmyelinating. Additional phenotypic specialization is suggested, however, by the preferential reinnervation of muscle pathways by motoneurons. To explore potential differences in...
7.
Le T, Aszmann O, Chen Y, Royall R, Brushart T
Exp Neurol . 2001 Feb; 167(1):126-32. PMID: 11161600
Youth is a strong predictor of functional recovery after peripheral nerve repair, while adulthood is commonly associated with poor outcome. Identification of the factors responsible for this difference could form...
8.
Al-Majed A, Brushart T, Gordon T
Eur J Neurosci . 2000 Dec; 12(12):4381-90. PMID: 11122348
Electrical stimulation promotes the speed and accuracy of motor axonal regeneration. The positive effects of stimulation are mediated at the cell body. Here we characterize the effect of electrical stimulation...
9.
Al-Majed A, Neumann C, Brushart T, Gordon T
J Neurosci . 2000 Mar; 20(7):2602-8. PMID: 10729340
Functional recovery is often poor despite the capacity for axonal regeneration in the peripheral nervous system and advances in microsurgical technique. Regeneration of axons in mixed nerve into inappropriate pathways...
10.
Dumanian G, McClinton M, Brushart T
J Hand Surg Am . 1999 Feb; 24(1):30-6. PMID: 10048513
We developed a new quantitative rat sciatic nerve model to test whether free fat grafts can reduce postoperative perineural scar formation. Epineurectomies of sciatic nerves were performed to create scar....