T L Petryshen
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Explore the profile of T L Petryshen including associated specialties, affiliations and a list of published articles.
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13
Citations
465
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Recent Articles
1.
Blokland G, Maleki N, Jovicich J, Mesholam-Gately R, DeLisi L, Turner J, et al.
Int J Clin Health Psychol
. 2024 Apr;
24(2):100458.
PMID: 38623146
Enlarged lateral ventricle (LV) volume and decreased volume in the corpus callosum (CC) are hallmarks of schizophrenia (SZ). We previously showed an inverse correlation between LV and CC volumes in...
2.
Durak O, de Anda F, Singh K, Leussis M, Petryshen T, Sklar P, et al.
Mol Psychiatry
. 2014 May;
20(3):388-97.
PMID: 24821222
Ankyrin-G is a scaffolding protein required for the formation of the axon initial segment in neurons. Recent genome-wide association studies and whole-exome sequencing have identified ANK3, the gene coding for...
3.
Del Re E, Bergen S, Mesholam-Gately R, Niznikiewicz M, Goldstein J, Woo T, et al.
Transl Psychiatry
. 2014 Jan;
4:e346.
PMID: 24424392
Several genes have recently been identified as risk factors for schizophrenia (SZ) by genome-wide association studies (GWAS), including ZNF804A which is thought to function in transcriptional regulation. However, the downstream...
4.
Leussis M, Frayne M, Saito M, Berry E, Aldinger K, Rockwell G, et al.
Genes Brain Behav
. 2009 Aug;
8(8):806-16.
PMID: 19694817
Prepulse inhibition (PPI) is a measure of sensorimotor gating, a pre-attentional inhibitory brain mechanism that filters extraneous stimuli. Prepulse inhibition is correlated with measures of cognition and executive functioning, and...
5.
Petryshen T, Sabeti P, Aldinger K, Fry B, Fan J, Schaffner S, et al.
Mol Psychiatry
. 2009 Mar;
15(8):810-5.
PMID: 19255578
Genetic variants in the brain-derived neurotrophic factor (BDNF) gene, predominantly the functional Val66Met polymorphism, have been associated with risk of bipolar disorder and other psychiatric disorders. However, not all studies...
6.
Petryshen T, Middleton F, Tahl A, Rockwell G, Purcell S, Aldinger K, et al.
Mol Psychiatry
. 2005 Sep;
10(12):1074-88, 1057.
PMID: 16172613
We previously performed a genome-wide linkage scan in Portuguese schizophrenia families that identified a risk locus on chromosome 5q31-q35. This finding was supported by meta-analysis of 20 other schizophrenia genome-wide...
7.
Petryshen T, Middleton F, Kirby A, Aldinger K, Purcell S, Tahl A, et al.
Mol Psychiatry
. 2004 Nov;
10(4):366-74, 328.
PMID: 15545978
Schizophrenia is a common, multigenic psychiatric disorder. Linkage studies, including a recent meta-analysis of genome scans, have repeatedly implicated chromosome 8p12-p23.1 in schizophrenia susceptibility. More recently, significant association with a...
8.
Pato C, Pato M, Kirby A, Petryshen T, Medeiros H, Carvalho C, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2004 Apr;
127B(1):30-4.
PMID: 15108176
As part of an extensive study in the Portuguese Island population of families with multiple patients suffering from bipolar disorder and schizophrenia, we performed an initial genome-wide scan of 16...
9.
Middleton F, Pato M, Gentile K, Morley C, Zhao X, Eisener A, et al.
Am J Hum Genet
. 2004 Apr;
74(5):886-97.
PMID: 15060841
We performed a linkage analysis on 25 extended multiplex Portuguese families segregating for bipolar disorder, by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay, the GeneChip Human Mapping 10K Array...
10.
Sklar P, Pato M, Kirby A, Petryshen T, Medeiros H, Carvalho C, et al.
Mol Psychiatry
. 2003 Dec;
9(2):213-8.
PMID: 14699422
Schizophrenia is a common psychiatric disorder with a complex genetic etiology. To understand the genetic basis of this syndrome in Portuguese Island populations, we performed a genome-wide scan of 29...