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T Klonisch

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Articles 46
Citations 650
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Recent Articles
1.
Yeganeh B, Ghavami S, Rahim M, Klonisch T, Halayko A, Coombs K
Biochim Biophys Acta Mol Cell Res . 2017 Nov; 1865(2):364-378. PMID: 29108912
Autophagy and apoptosis are two major interconnected host cell responses to viral infection, including influenza A virus (IAV). Thus, delineating these events could facilitate the development of better treatment options...
2.
Pathak K, Lambert P, Nason R, Klonisch T
Eur J Surg Oncol . 2016 Jun; 42(10):1491-6. PMID: 27265038
Objective: Thyroid prognostic nomogram can be applied across different histological types for predicting the individualized risk of death from thyroid cancer. The objective of this study was to compare the...
3.
Ghavami S, Cunnington R, Gupta S, Yeganeh B, Filomeno K, Freed D, et al.
Cell Death Dis . 2015 Mar; 6:e1696. PMID: 25789971
Transforming growth factor-β(1) (TGF-β(1)) is an important regulator of fibrogenesis in heart disease. In many other cellular systems, TGF-β(1) may also induce autophagy, but a link between its fibrogenic and...
4.
Ghavami S, Yeganeh B, Stelmack G, Kashani H, Sharma P, Cunnington R, et al.
Cell Death Dis . 2012 Jun; 3:e330. PMID: 22717585
3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) are cholesterol-lowering drugs that exert other cellular effects and underlie their beneficial health effects, including those associated with myocardial remodeling. We recently demonstrated that statins induces...
5.
King A, Collins F, Klonisch T, Sallenave J, Critchley H, Saunders P
Hum Reprod . 2009 Dec; 25(2):510-8. PMID: 19955102
Background: Human embryo implantation is regulated by estradiol (E2), progesterone and locally produced mediators including interleukin-1beta (IL-1beta). Interactions between the estrogen receptor (ER) and NF kappa B (NFkappaB) signalling pathways...
6.
Pocar P, Klonisch T, Brandsch C, Eder K, Frohlich C, Hoang-Vu C, et al.
Toxicol Sci . 2005 Nov; 89(2):408-14. PMID: 16291828
The Ah receptor (AhR) is a ligand transcription factor mediating toxic effects of chemicals such as dioxins. The 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) and the coplanar polychlorinated biphenyl 126 (PCB 126) are...
7.
Klonisch T, Mustafa T, Bialek J, Radestock Y, Holzhausen H, Dralle H, et al.
Ann N Y Acad Sci . 2005 Jun; 1041:449-61. PMID: 15956746
We investigated the expression of H1, H2 relaxin and INSL-3, mRNA and protein, and LGR7 and LGR8 transcripts in human C-cell hyperplasia, primary medullary thyroid carcinoma (MTC) tissues, MTC metastases,...
8.
Hombach-Klonisch S, Kehlen A, Fowler P, Huppertz B, Jugert J, Bischoff G, et al.
J Mol Endocrinol . 2005 Apr; 34(2):517-34. PMID: 15821114
Information on the regulation of steroid hormone receptors and their distinct functions within the human endometrial epithelium is largely unavailable. We have immortalized human primary endometrial epithelial cells (EECs) isolated...
9.
Pocar P, Fischer B, Klonisch T, Hombach-Klonisch S
Reproduction . 2005 Mar; 129(4):379-89. PMID: 15798013
The dioxin/aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor responsive to both natural and man-made environmental compounds. AhR and its nuclear partner ARNT are expressed in the female reproductive...
10.
Hombach-Klonisch S, Pocar P, Kietz S, Klonisch T
Curr Med Chem . 2005 Mar; 12(5):599-616. PMID: 15777215
Polyhalogenated aromatic arylhydrocarbons (PAHs) such as polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), the polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) are persistent lipophilic pollutants, which affect female fertility resulting...