T J M Helmerhorst
Overview
Explore the profile of T J M Helmerhorst including associated specialties, affiliations and a list of published articles.
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12
Citations
232
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Recent Articles
1.
Uijterwaal M, van Zummeren M, Kocken M, Luttmer R, Berkhof J, Witte B, et al.
Gynecol Oncol
. 2016 Jul;
143(1):135-142.
PMID: 27430395
Introduction: Recent studies have shown that CADM1/MAL-methylation testing detects high-grade CIN lesions with a high short-term progression risk for cervical cancer. Women treated for CIN2/3 are at risk of post-treatment...
2.
van der Marel J, van Baars R, Quint W, Berkhof J, Del Pino M, Torne A, et al.
BJOG
. 2014 Feb;
121(9):1117-26.
PMID: 24494663
Objective: To study colposcopic performance in diagnosing high-grade cervical intraepithelial neoplasia or cervical cancer (CIN2+ and CIN3+) using colposcopic characteristics and high-risk human papillomavirus (hrHPV) genotyping. Design: Cross-sectional multicentre study....
3.
Kocken M, Berkhof J, van Kemenade F, Louwers J, Zaal A, Nobbenhuis M, et al.
Br J Cancer
. 2012 Feb;
106(5):817-25.
PMID: 22333596
Background: Many studies have examined the short-term value of high-risk human papillomavirus (hrHPV) testing in predicting cumulative risk of cervical intraepithelial neoplasia grade 3 or cancer (CIN3+). This study focuses...
4.
van der Meide W, Snellenberg S, Meijer C, Baalbergen A, Helmerhorst T, van der Sluis W, et al.
Gynecol Oncol
. 2011 Jul;
123(1):116-22.
PMID: 21726894
Objective: Cervical adenocarcinoma (AdCA) and adenocarcinoma in situ (ACIS) are frequently missed in cytology-based screening programs. Testing for high-risk human papillomavirus (hrHPV) improves their detection, but novel ACIS/AdCA specific biomarkers...
5.
Heideman D, Snijders P, Berkhof J, Verheijen R, Helmerhorst T, Meijer C
BJOG
. 2008 Jul;
115(8):938-46.
PMID: 18651878
A novel approach for primary prevention of cervical cancer has become available by the discovery of efficient prophylactic human papillomavirus (HPV) vaccines based on virus-like particles. This review elaborates on...
6.
Overmeer R, Henken F, Snijders P, Claassen-Kramer D, Berkhof J, Helmerhorst T, et al.
J Pathol
. 2008 May;
215(4):388-97.
PMID: 18498117
We previously showed that silencing of TSLC1, recently renamed CADM1, is functionally involved in high-risk HPV-mediated cervical carcinogenesis. CADM1 silencing often results from promoter methylation. Here, we determined the extent...
7.
van Erp E, Heintz A, Helmerhorst T, Koster M, van Leeuwen F
Ned Tijdschr Geneeskd
. 2007 Jun;
151(21):1197-200.
PMID: 17557761
In 2007 the Dutch DESFonds (DES Fund) starts payment to victims of exposure to diethylstilbestrol in a collective settlement. This is unique in the world because the arrangement covers the...
8.
van Seters M, Ten Kate F, van Beurden M, Verheijen R, Meijer C, Burger M, et al.
J Clin Pathol
. 2006 May;
60(5):504-9.
PMID: 16714399
Background: Differentiated vulvar intraepithelial neoplasia (VIN) is presumed to be the precursor of invasive squamous cell carcinoma (SCC) of the vulva. It is commonly assumed that differentiated VIN is related...
9.
Bais A, Beckmann I, Lindemans J, Ewing P, Meijer C, Snijders P, et al.
J Clin Pathol
. 2005 Sep;
58(10):1096-100.
PMID: 16189158
Background: A shifted balance between T helper 1 (Th1)-type and Th2-type cytokines has been hypothesised in cervical dysplasia. Aims: To evaluate possible deregulation of the cytokine network by estimating the...
10.
Nobbenhuis M, Helmerhorst T, van den Brule A, Rozendaal L, Bezemer P, Voorhorst F, et al.
Br J Cancer
. 2002 Jun;
87(1):75-80.
PMID: 12085260
We followed 353 women referred with abnormal cervical cytology in a non-intervention cohort study. In 91 pregnant women we compared high-risk human papilloma virus rates in the subsequent trimesters and...