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T Hagenacker

Explore the profile of T Hagenacker including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 227
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Recent Articles
1.
Brakemeier S, Lipka J, Schlag M, Kleinschnitz C, Hagenacker T
J Neurol . 2024 Feb; 271(5):2649-2657. PMID: 38358553
Background: 5q-associated spinal muscular atrophy (SMA) is characterized by the progressive loss of motor neurons with consecutive weakness and atrophy of the limb, respiratory, and bulbar muscles. While trunk and...
2.
Lapp H, Freigang M, Hagenacker T, Weiler M, Wurster C, GuNTHER R
J Neurol . 2023 Jun; 270(9):4157-4178. PMID: 37289324
5q-associated spinal muscular atrophy (SMA) is a rare genetic disease caused by mutations in the SMN1 gene, resulting in a loss of functional SMN protein and consecutive degeneration of motor...
3.
Kruse T, Shamai S, Leflerova D, Wirth B, Heller R, Schloss N, et al.
Orphanet J Rare Dis . 2023 May; 18(1):103. PMID: 37138365
Background: Impairment of bulbar function in adult individuals with spinal muscular atrophy (SMA) usually is not assessed by established motor scores. Measurements of oral function including quantitative muscle and endurance...
4.
Hagenacker T, Schara-Schmidt U, Kleinschnitz C
Nervenarzt . 2022 May; 93(6):549-556. PMID: 35522309
Background: The 5q-associated spinal muscular atrophy (SMA) affects ~ 80-120 newborns annually. The disease is characterized by progressive paresis involving the bulbar and respiratory musculatures. The phenotypes are very heterogeneous...
5.
Stolte B, Bois J, Bolz S, Kizina K, Totzeck A, Schlag M, et al.
Eur J Neurol . 2020 Aug; 27(12):2586-2594. PMID: 32781490
Background And Purpose: In patients with spinal muscular atrophy (SMA), functional disease scores are frequently used to evaluate the course of the disease and the efficacy of treatment. The aim...
6.
Sansone V, Walter M, Attarian S, Delstanche S, Mercuri E, Lochmuller H, et al.
J Neuromuscul Dis . 2020 Jun; 7(4):523-534. PMID: 32538864
Spinal muscular atrophy (SMA) is a progressive autosomal recessive motor neuron disease which affects 1 in 6,000-10,000 live births, caused by loss of the survival motor neuron 1 gene (SMN1)....
7.
Oldenburg D, Guberina N, Stolte B, Kizina K, Stenzel E, Radbruch A, et al.
Neuroradiology . 2019 Mar; 61(5):565-574. PMID: 30868184
Purpose: To examine diagnostic reference levels (DRL) and achievable doses (AD) of image-guided and size-specific dose estimates (SSDE) and organ and effective doses of CT-guided intrathecal nusinersen administration to adult...
8.
Leo M, Schulte M, Schmitt L, Schafers M, Kleinschnitz C, Hagenacker T
Mediators Inflamm . 2017 Aug; 2017:2786427. PMID: 28831207
Transient receptor potential vanilloid-1 (TRPV1) is a nonselective cation channel, predominantly expressed in sensory neurons. TRPV1 is known to play an important role in the pathogenesis of inflammatory and neuropathic...
9.
Totzeck A, Stettner M, Hagenacker T
Eur J Neurol . 2017 Feb; 24(4):638-644. PMID: 28224702
Background And Purpose: Intravenous immunoglobulins (IVIGs) are a common therapy in patients with neuroinflammatory disorders, especially chronic inflammatory demyelinating polyradiculoneuropathy or Guillain-Barré syndrome. Hematological toxicities upon IVIG infusion are a...
10.
Leo M, Argalski S, Schafers M, Hagenacker T
Mediators Inflamm . 2015 Oct; 2015:124942. PMID: 26504355
Tumor necrosis factor- (TNF-) α is a proinflammatory cytokine involved in the development and maintenance of inflammatory and neuropathic pain. Its effects are mediated by two receptors, TNF receptor-1 (TNFR-1)...