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T Grodzicker

Explore the profile of T Grodzicker including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
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1.
Quinlan M, Whyte P, Grodzicker T
Mol Cell Biol . 1988 Aug; 8(8):3191-203. PMID: 2974923
The 12S protein encoded by the adenovirus E1A region induces cellular DNA synthesis in and proliferation and immortalization of primary rat epithelial cells in the presence or absence of serum....
2.
Cone R, Grodzicker T, Jaramillo M
Mol Cell Biol . 1988 Mar; 8(3):1036-44. PMID: 2966895
An epithelial cell-transforming virus could be of great use, both in the culture of epithelial cell lines and in the study of carcinogenesis. Since the adenoviral E1A gene has been...
3.
Quinlan M, Sullivan N, Grodzicker T
Proc Natl Acad Sci U S A . 1987 May; 84(10):3283-7. PMID: 2953026
Infection of primary baby rat kidney cells with an adenovirus variant that encodes only the 12S gene of the E1A region, adenovirus type 5 (Ad5) 12S, results in the production...
4.
Quinlan M, Grodzicker T
J Virol . 1987 Mar; 61(3):673-82. PMID: 3027395
Infection of primary baby rat kidney (BRK) cells with an adenovirus that carries an E1A 12S cDNA in place of the normal E1A region (adenovirus 5 [Ad5] 12S) resulted in...
5.
Mansour S, Grodzicker T, Tjian R
Mol Cell Biol . 1986 Jul; 6(7):2684-94. PMID: 3023944
We analyzed a set of adenovirus-simian virus 40 (SV40) hybrids in which the SV40 T antigen coding sequences are inserted downstream from the adenovirus major late promoter within the first,...
6.
Zerler B, Moran B, Maruyama K, Moomaw J, Grodzicker T, Ruley H
Mol Cell Biol . 1986 Mar; 6(3):887-99. PMID: 3022137
Plasmids expressing partial adenovirus early region 1A (E1A) coding sequences were tested for activities which facilitate in vitro establishment (immortalization) of primary baby rat kidney cells and which enable the...
7.
Moran E, Grodzicker T, Roberts R, Mathews M, Zerler B
J Virol . 1986 Mar; 57(3):765-75. PMID: 2936898
To distinguish the individual roles of the 13S, 12S, and 9S adenovirus E1A gene products, we isolated the corresponding cDNA clones and recombined them into both plasmids and viruses. Only...
8.
Yamada M, Lewis J, Grodzicker T
Proc Natl Acad Sci U S A . 1985 Jun; 82(11):3567-71. PMID: 2987934
We have constructed a recombinant adenovirus that carries the herpes simplex virus type I gene for thymidine kinase (EC 2.7.1.21) and expresses thymidine kinase under control of adenovirus major late...
9.
Mansour S, Grodzicker T, Tjian R
Proc Natl Acad Sci U S A . 1985 Mar; 82(5):1359-63. PMID: 2983341
We have used a generalized adenovirus vector system to express the three polyoma tumor (T) antigen proteins under the control of the adenovirus major late promoter. One hybrid virus, Ad-PySVR498,...
10.
White E, Grodzicker T, Stillman B
J Virol . 1984 Nov; 52(2):410-9. PMID: 6492256
The adenovirus mutant Ad2ts111 has been previously shown to contain a mutation in the early region 2A gene encoding the single-stranded-DNA-binding protein that results in thermolabile replication of virus DNA...