T Brett Kothe
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Explore the profile of T Brett Kothe including associated specialties, affiliations and a list of published articles.
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7
Citations
63
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0
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Recent Articles
1.
Becker S, Kothe T, Josephsen J, Jackson K, Williams H, Hillman N
Neonatology
. 2022 May;
119(4):474-482.
PMID: 35598595
Background: The combination of surfactant and budesonide has been shown to decrease BPD rates and severity. Budesonide may be released systemically from lungs, and the effects on the immature adrenal...
2.
Anderson C, Kothe T, Josephsen J, Sadiq F, Burleyson N, Williams H, et al.
J Perinatol
. 2021 May;
41(7):1681-1689.
PMID: 33986470
Background: The addition of budesonide to surfactant in very-low-birth-weight infants with less severe RDS decreased bronchopulmonary dysplasia (BPD) severity. Long-term neurodevelopmental follow-up was needed to monitor for systemic effects of...
3.
Kothe T, Sadiq F, Burleyson N, Williams H, Anderson C, Hillman N
Pediatr Res
. 2019 Nov;
87(5):940-945.
PMID: 31715622
Background: In preterm infants on moderately high ventilator support, the addition of budesonide to surfactant lowered bronchopulmonary dysplasia (BPD) rates by 20% without increased morbidity or mortality. The aim of...
4.
Hillman N, Kothe T, Schmidt A, Kemp M, Royse E, Fee E, et al.
Am J Physiol Lung Cell Mol Physiol
. 2019 Oct;
318(1):L41-L48.
PMID: 31617728
Mechanical ventilation from birth with normal tidal volumes (V) causes lung injury and systemic responses in preterm sheep. The addition of budesonide to surfactant therapy decreases these injury markers. Budesonide...
5.
Kothe T, Kemp M, Schmidt A, Royse E, Salomone F, Clarke M, et al.
Am J Physiol Lung Cell Mol Physiol
. 2019 Mar;
316(5):L888-L893.
PMID: 30838863
Mechanical ventilation with normal tidal volumes (V) causes lung and systemic inflammation in preterm sheep. Mechanical ventilation is associated with bronchopulmonary dysplasia (BPD) in preterm infants, and the addition of...
6.
Kothe T, Royse E, Kemp M, Usuda H, Saito M, Musk G, et al.
PLoS One
. 2018 Jul;
13(7):e0200713.
PMID: 30005089
Background: Epidermal growth factor receptor (EGFR) is important for airway branching and lung maturation. Mechanical ventilation of preterm lambs causes increases in EGFR and EGFR ligand mRNA in the lung....
7.
Kothe T, Royse E, Kemp M, Schmidt A, Salomone F, Saito M, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Apr;
315(2):L193-L201.
PMID: 29671605
Mechanical ventilation causes lung injury and systemic inflammatory responses in preterm sheep and is associated with bronchopulmonary dysplasia (BPD) in preterm infants. Budesonide added to surfactant decreased BPD by 20%...