T Aiuchi
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Explore the profile of T Aiuchi including associated specialties, affiliations and a list of published articles.
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29
Citations
179
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Recent Articles
1.
Aiuchi T, Shirane Y, Kinemuchi H, Arai Y, Kim S, Nakaya K, et al.
Neurochem Int
. 2010 May;
17(1):59-65.
PMID: 20504603
The effects of the 1-methyl-4-phenylpyridinium ion (MPP(+)) and some structurally related compounds on mitochondrial respiration and lactate production in mouse brain synaptosomes were studied with and without tetraphenylboron (TPB(?)), an...
2.
Aiuchi T, Shirane Y, Kinemuchi H, Arai Y, Nakaya K, Nakamura Y
Neurochem Int
. 2010 May;
12(4):525-31.
PMID: 20501261
The effect of tetraphenylboron (TPB(?)), an activator of a membrane transport of lipophilic cations, on the inhibition of mouse liver mitochondrial respiration induced by a neurotoxin, 1-methyl-4-phenylpyridinium ion (MPP(+)), and...
3.
Iwama K, Nakajo S, Aiuchi T, Nakaya K
Int J Cancer
. 2001 Apr;
92(4):518-26.
PMID: 11304686
The mechanism of the induction of apoptosis by arsenic trioxide (As2O3), which was demonstrated recently to be an effective inducer of apoptosis in patients with leukemia, was examined in detail...
4.
Masuda Y, Nakaya M, Aiuchi T, Hashimoto S, Nakajo S, Nakaya K
Leuk Res
. 2000 Nov;
24(11):937-50.
PMID: 11086177
In the present study, we investigated the effects of geranylgeraniol (GGO), a potent inducer of apoptosis in various lines of human tumor cells, on signal transduction cascades involved in apoptosis...
5.
Nakaya M, Masuda Y, Mihara S, Aiuchi T, Nakajo S, Nakaya K
Anticancer Res
. 2000 Mar;
19(6B):5063-8.
PMID: 10697511
Affinity labeling showed that active caspases with molecular masses of 20 kDa, 19 kDa, and 17 kDa were formed upon treatment of human leukemia U937 cells with GGO. These caspases...
6.
Kawazoe N, Aiuchi T, Masuda Y, Nakajo S, Nakaya K
J Biochem
. 1999 Jul;
126(2):278-86.
PMID: 10423518
In an attempt to characterize the mechanisms that are operative at the early stages of the induction of apoptosis by bufalin, a component of the traditional Chinese medicine chan'su, we...
7.
Hashimoto S, Xu M, Masuda Y, Aiuchi T, Nakajo S, Cao J, et al.
J Biochem
. 1999 Jan;
125(1):17-23.
PMID: 9880790
beta-Hydroxyisovalerylshikonin (beta-HIVS), which was isolated from the plant, Lithospermium radix, inhibited the growth of various lines of cancer cells derived from human solid tumors at low concentrations between 10(-8) and...
8.
Zinc ions prevent processing of caspase-3 during apoptosis induced by geranylgeraniol in HL-60 cells
Aiuchi T, Mihara S, Nakaya M, Masuda Y, Nakajo S, Nakaya K
J Biochem
. 1998 Aug;
124(2):300-3.
PMID: 9685718
Geranylgeraniol (GGO) at 50 microM induces apoptosis in HL-60 cells. We examined the effects of Zn2+ ions on this process. Treatment of HL-60 cells with Zn2+ ions inhibited subsequent GGO-induced...
9.
Masuda Y, Yoda M, Ohizumi H, Aiuchi T, Watabe M, Nakajo S, et al.
Int J Cancer
. 1997 May;
71(4):691-7.
PMID: 9178828
In a previous study, we showed that geranylgeraniol (GGO) is a potent inducer of apoptosis in human leukemia cells, including HL60 promyelocytic leukemia cells. The present study describes the effects...
10.
Sakagami H, Satoh K, Aiuchi T, Nakaya K, Takeda M
Anticancer Res
. 1997 Mar;
17(2A):1213-6.
PMID: 9137474
Alkali-lignin, lignin sulfonate or protein-bound polysaccharide (PSK) significantly enhanced the ascorbyl radical intensity and cytotoxic activity of ascorbate, but inhibited the intracellular incorporation of [14C]ascorbic acid. These natural products also...