T Aigner
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Explore the profile of T Aigner including associated specialties, affiliations and a list of published articles.
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Articles
137
Citations
4450
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Recent Articles
1.
Klinger P, Lukassen S, Ferrazzi F, Ekici A, Hotfiel T, Swoboda B, et al.
Biomed Res Int
. 2017 Feb;
2017:7183516.
PMID: 28191465
To investigate the expression and target genes of pigment epithelium-derived factor (PEDF) in cartilage and chondrocytes, respectively. We analyzed the expression pattern of PEDF in different human cartilaginous tissues including...
2.
Schone M, Mannicke N, Somerson J, Marquass B, Henkelmann R, Mochida J, et al.
Eur Cell Mater
. 2016 Feb;
31:119-35.
PMID: 26853622
Objective and sensitive assessment of cartilage repair outcomes lacks suitable methods. This study investigated the feasibility of 3D ultrasound biomicroscopy (UBM) to quantify cartilage repair outcomes volumetrically and their correlation...
3.
Rose J, Soder S, Skhirtladze C, Schmitz N, Gebhard P, Sesselmann S, et al.
Osteoarthritis Cartilage
. 2012 Jun;
20(9):1020-8.
PMID: 22659602
Objective: The initiation/progression factors of osteoarthritic (OA) cartilage degeneration and the involved biological mechanisms remain rather enigmatic. One core reason for this might be a cellular senescence-like phenotype of OA...
4.
Soder S, Aigner T
Pathologe
. 2011 Apr;
32(3):183-92.
PMID: 21499759
Degenerative disorders of the musculoskeletal system, in particular osteoarthritis, are among the most common diseases of the elderly and their importance in an aging society is continuously increasing. Correspondingly, many...
5.
Marquass B, Somerson J, Hepp P, Aigner T, Schwan S, Bader A, et al.
J Orthop Res
. 2010 Oct;
28(12):1586-99.
PMID: 20973061
Mesenchymal stem cells (MSC) are increasingly replacing chondrocytes in tissue engineering based research for treatment of osteochondral defects. The aim of this work was to determine whether repair of critical-size...
6.
Giovannini S, Diaz-Romero J, Aigner T, Heini P, Mainil-Varlet P, Nesic D
Eur Cell Mater
. 2010 Oct;
20:245-59.
PMID: 20925023
Cell therapies for articular cartilage defects rely on expanded chondrocytes. Mesenchymal stem cells (MSC) represent an alternative cell source should their hypertrophic differentiation pathway be prevented. Possible cellular instruction between...
7.
Pritzker K, Aigner T
Osteoarthritis Cartilage
. 2010 Sep;
18 Suppl 3:S7-9.
PMID: 20864025
Unifying terminology used to describe morphologic features is a very important endeavour to assure comparability of work and papers on osteoarthritis animal models. In this editorial an attempt is presented...
8.
Aigner T, Cook J, Gerwin N, Glasson S, Laverty S, Little C, et al.
Osteoarthritis Cartilage
. 2010 Sep;
18 Suppl 3:S2-6.
PMID: 20864020
Animal model systems represent an important adjunct and surrogate for studies of osteoarthritis (OA) in humans. They provide a means to study OA pathophysiology as well as aid in the...
9.
Schmitz N, Laverty S, Kraus V, Aigner T
Osteoarthritis Cartilage
. 2010 Sep;
18 Suppl 3:S113-6.
PMID: 20864017
Histological and histochemical methods are important tools in the evaluation of joint tissue samples for degenerative joint diseases, both in humans and in animal models. In this respect, standardized, simple,...
10.
Adler D, Aigner T, von Salis-Soglio G, Gutberlet M, Heyde C
Orthopade
. 2010 Sep;
39(11):1065-70.
PMID: 20809161
Nora's lesion, also known as "bizarre parosteal osteochondromatous proliferation" (BPOP), was first described in 1983 by the pathologist Nora. This lesion is defined as a proliferation of the bone. In...