T A Gardiner
Overview
Explore the profile of T A Gardiner including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
1034
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Recent Articles
1.
Ding J, Strachan M, Fowkes F, Wong T, MacGillivray T, Patton N, et al.
Diabetologia
. 2011 Apr;
54(7):1653-62.
PMID: 21455727
Aims/hypothesis: Retinal vascular calibre changes may reflect early subclinical microvascular disease in diabetes. Because of the considerable homology between retinal and cerebral microcirculation, we examined whether retinal vascular calibre, as...
2.
Abdullah H, Earle J, Gardiner T, Tangy F, Cosby S
Neuropathol Appl Neurobiol
. 2009 Jun;
35(5):473-86.
PMID: 19490430
Aims: Infection of the mouse central nervous system with wild type (WT) and vaccine strains of measles virus (MV) results in lack of clinical signs and limited antigen detection. It...
3.
Curtis T, Gardiner T, Stitt A
Eye (Lond)
. 2009 May;
23(7):1496-508.
PMID: 19444297
Retinopathy is a major complication of diabetes mellitus and this condition remains a leading cause of blindness in the working population of developed countries. As diabetic retinopathy progresses a range...
4.
Zhang X, Lai Y, McCance D, Uchida K, McDonald D, Gardiner T, et al.
Diabetologia
. 2008 Jul;
51(9):1723-30.
PMID: 18587559
Aims/hypothesis: Recent studies suggest that oxidative stress should be monitored alongside HbA(1c) to identify subgroups of diabetic patients at high risk of initiation or progression of retinopathy. The acrolein-derived advanced...
5.
Bhatwadekar A, Glenn J, Figarola J, Scott S, Gardiner T, Rahbar S, et al.
Br J Ophthalmol
. 2008 Jan;
92(4):545-7.
PMID: 18211931
Background: Diabetic retinopathy is associated with accumulation of advanced glycation end products in the retinal microvasculature. LR-90 is an effective multistage inhibitor of advanced glycation with renoprotective and anti-inflammatory properties....
6.
McGahon M, Dawicki J, Arora A, Simpson D, Gardiner T, Stitt A, et al.
Am J Physiol Heart Circ Physiol
. 2006 Oct;
292(2):H1001-8.
PMID: 17040965
Little is known about the molecular characteristics of the voltage-activated K(+) (K(v)) channels that underlie the A-type K(+) current in vascular smooth muscle cells of the systemic circulation. We investigated...
7.
Konopatskaya O, Churchill A, Harper S, Bates D, Gardiner T
Mol Vis
. 2006 Jun;
12:626-32.
PMID: 16735996
Purpose: Hypoxia driven ocular angiogenesis occurs in a range of ischemic retinopathies including proliferative diabetic retinopathy and retinopathy of prematurity. These conditions are initiated and sustained by hypoxia dependent vascular...
8.
Brankin B, Campbell M, Canning P, Gardiner T, Stitt A
Exp Eye Res
. 2005 Jun;
81(1):22-31.
PMID: 15978251
Recent evidence indicates that the anti-angiogenic peptide endostatin may modulate some of the vasomodulatory effects of vascular endothelial growth factor (VEGF) in the retina, including reduction of blood retinal barrier...
9.
Stitt A, Hughes S, Canning P, Lynch O, Cox O, Frizzell N, et al.
Diabetologia
. 2004 Oct;
47(10):1735-46.
PMID: 15502926
Aims/hypothesis: Premature death of retinal pericytes is a pathophysiological hallmark of diabetic retinopathy. Among the mechanisms proposed for pericyte death is exposure to AGE, which accumulate during diabetes. The current...
10.
Mahon G, Anderson H, Gardiner T, McFarlane S, Archer D, Stitt A
Curr Eye Res
. 2004 Jul;
28(4):277-84.
PMID: 15259297
Chronic use of chloroquine has been shown to induce numerous pathophysiological defects in the retina. This drug has the ability to alter pH of intracellular compartments and lysosomal function of...