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Sytze Brandenburg

Explore the profile of Sytze Brandenburg including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 386
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Recent Articles
1.
Malimban J, Ludwig F, Lathouwers D, Staring M, Verhaegen F, Brandenburg S
Phys Med Biol . 2024 Oct; 69(21). PMID: 39433066
The integration of proton beamlines with x-ray imaging/irradiation platforms has opened up possibilities for image-guided Bragg peak irradiations in small animals. Such irradiations allow selective targeting of normal tissue substructures...
2.
Radstake W, Parisi A, Miranda S, Gautam K, Vermeesen R, Rehnberg E, et al.
Sci Rep . 2024 May; 14(1):10400. PMID: 38710823
Without the protective shielding of Earth's atmosphere, astronauts face higher doses of ionizing radiation in space, causing serious health concerns. Highly charged and high energy (HZE) particles are particularly effective...
3.
Olivari F, van Goethem M, Brandenburg S, van der Graaf E
Phys Med . 2023 Jul; 112:102636. PMID: 37494764
Purpose: To assess the feasibility of a proton radiography (pRG) system based on a single thin pixelated detector for water-equivalent path length (WEPL) and relative stopping power (RSP) measurements. Methods:...
4.
Radstake W, Gautam K, Miranda S, Vermeesen R, Tabury K, Rehnberg E, et al.
Cells . 2023 Jan; 12(2). PMID: 36672184
Human spaceflight is associated with several health-related issues as a result of long-term exposure to microgravity, ionizing radiation, and higher levels of psychological stress. Frequent reported skin problems in space...
5.
Seller Oria C, Free J, Marmitt G, Knausl B, Brandenburg S, Knopf A, et al.
Med Phys . 2023 Jan; 50(3):1756-1765. PMID: 36629844
Background: Proton radiography (PR) uses highly energetic proton beams to create images where energy loss is the main contrast mechanism. Water-equivalent path length (WEPL) measurements using flat panel PR (FP-PR)...
6.
Kretschmer J, Brodbek L, Looe H, van der Graaf E, Jan van Goethem M, Kiewiet H, et al.
Phys Med Biol . 2022 Jun; 67(14). PMID: 35697024
. Point detector measurements in proton fields are perturbed by the volume effect originating from geometrical volume-averaging within the extended detector's sensitive volume and density perturbations by non-water equivalent detector...
7.
Malimban J, Lathouwers D, Qian H, Verhaegen F, Wiedemann J, Brandenburg S, et al.
Sci Rep . 2022 Feb; 12(1):1822. PMID: 35110676
For image-guided small animal irradiations, the whole workflow of imaging, organ contouring, irradiation planning, and delivery is typically performed in a single session requiring continuous administration of anaesthetic agents. Automating...
8.
Qian H, Hoebe R, Faas M, Jan van Goethem M, van der Graaf E, Meyer C, et al.
Sci Rep . 2021 Jul; 11(1):14528. PMID: 34267233
Cellular responses to DNA double-strand breaks (DSBs) not only promote genomic integrity in healthy tissues, but also largely determine the efficacy of many DNA-damaging cancer treatments, including X-ray and particle...
9.
Patera V, Prezado Y, Azaiez F, Battistoni G, Bettoni D, Brandenburg S, et al.
Front Phys . 2020 Nov; 8:00380. PMID: 33224942
Biomedical applications at high-energy particle accelerators have always been an important section of the applied nuclear physics research. Several new facilities are now under constructions or undergoing major upgrades. While...
10.
Ozoemelam I, van der Graaf E, van Goethem M, Kapusta M, Zhang N, Brandenburg S, et al.
Phys Med Biol . 2020 Jul; 65(24):245013. PMID: 32650323
Compared to photon therapy, proton therapy allows a better conformation of the dose to the tumor volume with reduced radiation dose to co-irradiated tissues. In vivo verification techniques including positron...