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Sylwia Bujkiewicz

Explore the profile of Sylwia Bujkiewicz including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 353
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Recent Articles
1.
Wheaton L, Bujkiewicz S
Int J Technol Assess Health Care . 2025 Feb; 41(1):e11. PMID: 39967232
Objectives: Surrogate endpoints, used to substitute for and predict final clinical outcomes, are increasingly being used to support submissions to health technology assessment agencies. The increase in the use of...
2.
Zhang L, Bujkiewicz S, Jackson D
BMC Med Res Methodol . 2024 Nov; 24(1):287. PMID: 39567920
Background: The concept of the population is of fundamental importance in epidemiology and statistics. In some instances, it is not possible to sample directly from the population of interest. Weighting...
3.
Singh J, Anwer S, Palmer S, Saramago P, Thomas A, Dias S, et al.
Med Decis Making . 2024 Nov; 45(1):17-33. PMID: 39555661
Background: Multi-indication cancer drugs receive licensing extensions to include additional indications, as trial evidence on treatment effectiveness accumulates. We investigate how sharing information across indications can strengthen the inferences supporting...
4.
Musto L, Smith A, Pepper C, Bujkiewicz S, Bown M
Br J Surg . 2024 Sep; 111(9). PMID: 39287492
Background: This systematic review aimed to investigate the current state of risk prediction for abdominal aortic aneurysm in the literature, identifying and comparing published models and describing their performance and...
5.
Manyara A, Davies P, Stewart D, Weir C, Young A, Blazeby J, et al.
BMJ . 2024 Jul; 386:e078524. PMID: 38981645
No abstract available.
6.
Manyara A, Davies P, Stewart D, Weir C, Young A, Blazeby J, et al.
BMJ . 2024 Jul; 386:e078525. PMID: 38981624
No abstract available.
7.
Wheaton L, Jackson D, Bujkiewicz S
Res Synth Methods . 2024 Feb; 15(4):543-560. PMID: 38316618
During drug development, evidence can emerge to suggest a treatment is more effective in a specific patient subgroup. Whilst early trials may be conducted in biomarker-mixed populations, later trials are...
8.
Zhang L, Bujkiewicz S, Jackson D
Res Synth Methods . 2023 Dec; 15(2):227-241. PMID: 38104969
Simulated treatment comparison (STC) is an established method for performing population adjustment for the indirect comparison of two treatments, where individual patient data (IPD) are available for one trial but...
9.
Umemneku-Chikere C, Wheaton L, Poad H, Ray D, Andrade I, Khan S, et al.
J Clin Epidemiol . 2023 Nov; 164():96-103. PMID: 37918640
Objectives: We aimed to develop a network meta-analytic model for the evaluation of treatment effectiveness within predictive biomarker subgroups, by combining evidence from individual participant data (IPD) from digital sources...
10.
Ciani O, Manyara A, Davies P, Stewart D, Weir C, Young A, et al.
EClinicalMedicine . 2023 Oct; 65:102283. PMID: 37877001
Background: Interventional trials that evaluate treatment effects using surrogate endpoints have become increasingly common. This paper describes four linked empirical studies and the development of a framework for defining, interpreting...