Sylvia M Dobbs
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Explore the profile of Sylvia M Dobbs including associated specialties, affiliations and a list of published articles.
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18
Citations
268
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Recent Articles
1.
Wang W, Smith M, Ellis R, Savio A, Nevel A, Umamahesan C, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684838
Epidemiological and eradication trial evidence indicates that , a major causative factor in peptic ulcer and gastric cancer, is a driver of the hypokinesia of Parkinson's disease (PD). Psychological (cognitive...
2.
Wang W, Baker K, Umamahesan C, Gilmour S, Charlett A, Taylor D, et al.
J Clin Med
. 2023 Oct;
12(20).
PMID: 37892637
We question whether bradyphrenia, slowing of cognitive processing not explained by depression or a global cognitive assessment, is a nosological entity in idiopathic parkinsonism (IP). The time taken to break...
3.
Augustin A, Le Guennec A, Umamahesan C, Kendler-Rhodes A, Tucker R, Chekmeneva E, et al.
Clin Transl Med
. 2023 Jan;
13(1):e1152.
PMID: 36588088
Background: Gut-brain axis is widely implicated in the pathophysiology of Parkinson's disease (PD). We take an integrated approach to considering the gut as a target for disease-modifying intervention, using continuous...
4.
Tucker R, Augustin A, Hayee B, Bjarnason I, Taylor D, Weller C, et al.
J Clin Med
. 2020 Jul;
9(7).
PMID: 32650535
Interest in an aetiopathogenic role for in neuropsychiatric diseases started with idiopathic parkinsonism (IP), where the cardinal signs can be assessed objectively. This systematic review, using an EMBASE database search,...
5.
Tucker R, Ryan S, Hayee B, Bjarnason I, Augustin A, Umamahesan C, et al.
J Clin Med
. 2020 Jun;
9(6).
PMID: 32575365
Depression is associated with constipation within and outside Parkinson's disease (PD). Since inefficient cognitive-processing (bradyphrenia) features in PD and an enterokinetic agent improved cognitive performance in healthy individuals, bradyphrenia may...
6.
Augustin A, Savio A, Nevel A, Ellis R, Weller C, Taylor D, et al.
Front Med (Lausanne)
. 2019 Sep;
6:188.
PMID: 31555648
has been implicated in the pathogenesis of Parkinson's disease (PD). Its eradication, in a randomized placebo-controlled trial, improved PD hypokinesia. species zoonosis might explain excess mortality from PD and non-Hodgkin...
7.
Augustin A, Charlett A, Weller C, Dobbs S, Taylor D, Bjarnason I, et al.
Br J Clin Pharmacol
. 2016 Apr;
82(2):441-50.
PMID: 27062674
Aim: To estimate whether laxatives prescribed for constipation in Parkinson's disease (PD) could moderate rigidity. Constipation predates diagnosis of PD by decades. Deposition of misfolded protein may begin in the...
8.
Dobbs S, Dobbs R, Weller C, Charlett A, Augustin A, Taylor D, et al.
J Neurovirol
. 2015 Jun;
22(1):22-32.
PMID: 26092111
We seek an aetiopathogenic model for the spectrum of Parkinson's disease (PD), functional bowel disease, depression and cognitive impairment. The adopted concept is that systemic immuno-inflammatory processes mediate neuro-inflammation. The...
9.
Dobbs S, Charlett A, Dobbs R, Weller C, Iguodala O, Smee C, et al.
Helicobacter
. 2013 Jan;
18(3):187-96.
PMID: 23336966
Background: Following Helicobacter pylori eradication in a placebo-controlled trial, the hypokinesia of idiopathic parkinsonism improved but flexor rigidity worsened. Methods: We surveyed the effect of all antimicrobial prescriptions in 66...
10.
Dobbs R, Charlett A, Dobbs S, Weller C, Ibrahim M, Iguodala O, et al.
Gut Pathog
. 2012 Oct;
4(1):12.
PMID: 23083400
Unlabelled: Background: Following Helicobacter pylori eradication in idiopathic parkinsonism (IP), hypokinesia improved but flexor-rigidity increased. Small intestinal bacterial-overgrowth (SIBO) is a candidate driver of the rigidity: hydrogen-breath-test-positivity is common in...