Sylvia Lam
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Explore the profile of Sylvia Lam including associated specialties, affiliations and a list of published articles.
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10
Citations
76
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Recent Articles
1.
Hohert G, Myers R, Lam S, Vertikov A, Lee A, Lam S, et al.
J Biomed Opt
. 2020 Oct;
25(10).
PMID: 33084256
Significance: Diagnosis of suspicious lung nodules requires precise collection of relevant biopsies for histopathological analysis. Using optical coherence tomography and autofluorescence imaging (OCT-AFI) to improve diagnostic yield in parts of...
2.
Bodenschatz N, Poh C, Lam S, Lane P, Guillaud M, MacAulay C
J Biomed Opt
. 2017 Aug;
22(8):1-10.
PMID: 28823113
Dual-mode endomicroscopy is a diagnostic tool for early cancer detection. It combines the high-resolution nuclear tissue contrast of fluorescence endomicroscopy with quantified depth-dependent epithelial backscattering as obtained by diffuse optical...
3.
Bailey M, Verma N, Fradkin L, Lam S, MacAulay C, Poh C, et al.
J Biomed Opt
. 2017 Jun;
22(6):65002.
PMID: 28609512
We developed a multifiber optical probe for oblique polarized reflectance spectroscopy (OPRS) in vivo and evaluated its performance in detection of dysplasia in the oral cavity. The probe design allows...
4.
Schlosser C, Bodenschatz N, Lam S, Lee M, McAlpine J, Miller D, et al.
J Biomed Opt
. 2016 Dec;
21(12):126011.
PMID: 27999860
Current diagnostic capabilities and limitations of fluorescence endomicroscopy in the cervix are assessed by qualitative and quantitative image analysis. Four cervical tissue types are investigated: normal columnar epithelium, normal and...
5.
Wei R, Li Q, Lam S, Leung J, Cheung C, Zhang X, et al.
Behav Brain Res
. 2016 Aug;
314:190-8.
PMID: 27498245
Rationale: Rodents exposed to valproic acid (VPA) in prenatal life exhibit post-natal characteristics analogous to autism spectrum disorder (ASD). Many previous studies used relatively high doses of VPA during early...
6.
Bodenschatz N, Lam S, Carraro A, Korbelik J, Miller D, McAlpine J, et al.
J Biomed Opt
. 2016 Jun;
21(6):66001.
PMID: 27251077
A fiber optic imaging approach is presented using structured illumination for quantification of almost pure epithelial backscattering. We employ multiple spatially modulated projection patterns and camera-based reflectance capture to image...
7.
Zhang X, Li Q, Zhang M, Lam S, Sham P, Bu B, et al.
PLoS One
. 2015 Dec;
10(12):e0145638.
PMID: 26716999
Oxytocin has been suggested as a promising new treatment for neurodevelopmental disorders. However, important gaps remain in our understanding of its mode of action, in particular, to what extent oxytocin...
8.
Contaldo M, Poh C, Guillaud M, Lucchese A, Rullo R, Lam S, et al.
Oral Surg Oral Med Oral Pathol Oral Radiol
. 2013 Nov;
116(6):752-8.
PMID: 24237726
Objective: This pilot study evaluated the baseline effectiveness of a novel handheld fluorescent confocal microscope (FCM) specifically developed for oral mucosa imaging and compared the results with the literature. Study...
9.
Lane P, Lam S, Follen M, MacAulay C
Gend Med
. 2012 Feb;
9(1 Suppl):S78-82.e1-8.
PMID: 22340643
Background: Optical spectroscopy and imaging devices are being developed and tested for the screening and diagnosis of cancer and precancer in multiple organ sites. Objective: The aim of the study...
10.
Deng M, Lam S, Meyer U, Feldon J, Li Q, Wei R, et al.
PLoS One
. 2011 Feb;
6(2):e16638.
PMID: 21347362
Background: Maternal immune activation (MIA) during prenatal life is a risk factor for neurodevelopmental disorders including schizophrenia and autism. Such conditions are associated with alterations in fronto-subcortical circuits, but their...