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Sylvia A Sapula

Explore the profile of Sylvia A Sapula including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 76
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Recent Articles
1.
Sapula S, Wang Y, Hart B, Whittall J, Venter H
Biochem J . 2025 Jan; 482(3). PMID: 39804574
The Stenotrophomonas maltophilia L2 cephalosporinase is one of two beta-lactamases that afford S. maltophilia beta-lactam resistance. With the overuse of beta-lactams, selective pressures have contributed to the evolution of these...
2.
Siderius N, Sapula S, Hart B, Hutchings J, Venter H
Microbiol Res . 2024 Aug; 288:127867. PMID: 39163716
Background: Enterobacter species are included among the normal human gut microflora and persist in a diverse range of other environmental niches. They have become important opportunistic nosocomial pathogens known to...
3.
Sapula S, Hart B, Siderius N, Amsalu A, Blaikie J, Venter H
Microbiologyopen . 2024 Apr; 13(3):e1409. PMID: 38682784
Stenotrophomonas maltophilia is a multidrug-resistant (MDR), Gram-negative bacterium intrinsically resistant to beta-lactams, including last-resort carbapenems. As an opportunistic pathogen, it can cause serious healthcare-related infections. This study assesses the prevalence,...
4.
Blaikie J, Sapula S, Siderius N, Hart B, Amsalu A, Leong L, et al.
Microorganisms . 2024 Apr; 12(4). PMID: 38674695
Antimicrobial-resistant is one of the predominant pathogens in healthcare settings. However, the prevalence and resistome of this organism within residential aged care facilities (RACFs), which are potential hotspots for antimicrobial...
5.
Wang Y, Sapula S, Whittall J, Blaikie J, Lomovskaya O, Venter H
Commun Biol . 2024 Mar; 7(1):282. PMID: 38454015
The increasing rate of carbapenem-resistant bacteria within healthcare environments is an issue of great concern that needs urgent attention. This resistance is driven by metallo-β-lactamases (MBLs), which can catalyse the...
6.
Sapula S, Amsalu A, Whittall J, Hart B, Siderius N, Nguyen L, et al.
Microbiol Spectr . 2023 Oct; 11(6):e0073123. PMID: 37787536
Antimicrobial resistance (AMR) is a global threat that imposes a heavy burden on our health and economy. Residential aged care facilities (RACFs), where frequent inappropriate antibiotic use creates a selective...
7.
Alhamami T, Roy Chowdhury P, Venter H, Veltman T, Truswell A, Abraham S, et al.
Vet Microbiol . 2023 May; 283:109773. PMID: 37201306
Pasteurella multocida causes a range of diseases in many host species throughout the world, including bovine respiratory disease (BRD) which is predominantly seen in feedlot cattle. This study assessed genetic...
8.
Amsalu A, Sapula S, Whittall J, Hart B, Bell J, Turnidge J, et al.
Microb Genom . 2021 Dec; 7(12). PMID: 34919514
Carbapenems are potent broad-spectrum β-lactam antibiotics reserved for the treatment of serious infections caused by multidrug-resistant bacteria such as . The surge in resistant to carbapenems is an urgent threat,...
9.
Sapula S, Whittall J, Pandopulos A, Gerber C, Venter H
Sci Total Environ . 2021 May; 785:147270. PMID: 33940413
Wastewater-based epidemiology is currently being utilized to monitor the dissemination of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), on a population scale. The detection of SARS-CoV-2 in wastewater is...
10.
Amsalu A, Sapula S, De Barros Lopes M, Hart B, Nguyen A, Drigo B, et al.
Microorganisms . 2020 Oct; 8(11). PMID: 33114277
is an opportunistic pathogen displaying high intrinsic antimicrobial resistance and the ability to thrive in different ecological environments. In this study, the ability of to develop simultaneous resistance to multiple...