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Svenja Gaedcke

Explore the profile of Svenja Gaedcke including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 71
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Recent Articles
1.
Hilberink L, Wehage P, Pashai Fakhri M, Gaedcke S, DeLuca D, Mattis P, et al.
Pneumologie . 2025 Feb; 79(3):229-235. PMID: 39961349
Auscultation is one of the key medical skills in physical examination. The main problem with auscultation is the lack of objectivity of the findings and great dependence on the experience...
2.
Ackermann M, Saleh F, Abdin S, Rafiei Hashtchin A, Gensch I, Golgath J, et al.
Stem Cell Res Ther . 2024 Jun; 15(1):171. PMID: 38886860
Background: There is a significant demand for intermediate-scale bioreactors in academic and industrial institutions to produce cells for various applications in drug screening and/or cell therapy. However, the application of...
3.
Jirmo A, Grychtol R, Gaedcke S, Liu B, DeStefano S, Happle C, et al.
Front Immunol . 2023 May; 14:1127485. PMID: 37251386
A single population of interferon-regulatory factor 8 (Irf8)-dependent conventional dendritic cell (cDC type1) is considered to be responsible for both immunogenic and tolerogenic responses depending on the surrounding cytokine ....
4.
Pienkowska K, Pust M, Gessner M, Gaedcke S, Thavarasa A, Rosenboom I, et al.
Microbiol Spectr . 2023 Mar; :e0363322. PMID: 36892308
The microbial metagenome in cystic fibrosis (CF) airways was investigated by whole-genome shotgun sequencing of total DNA isolated from nasal lavage samples, oropharyngeal swabs, and induced sputum samples collected from...
5.
Grychtol R, Riemann L, Gaedcke S, Liu B, DeLuca D, Forster R, et al.
J Allergy Clin Immunol . 2023 Feb; 151(6):1525-1535.e4. PMID: 36804993
Background: The Asthma Severity Scoring System (ASSESS) quantifies asthma severity in adolescents and adults. Scale performance in children younger than 12 years is unknown. Objective: To validate the ASSESS score...
6.
Albrecht M, Halle O, Gaedcke S, Pallenberg S, Camargo Neumann J, Witt M, et al.
Clin Transl Immunology . 2022 Jun; 11(6):e1398. PMID: 35757569
Objectives: The contribution of adaptive innate lymphocytes to IL-17A and IL-22 secretion at the end stage of chronic lung diseases remains largely unexplored. In order to uncover tissue- and disease-specific...
7.
Gaedcke S, Sinning J, Dittrich-Breiholz O, Haller H, Soerensen-Zender I, Liao C, et al.
Am J Physiol Renal Physiol . 2022 May; 323(2):F171-F181. PMID: 35635323
The kidney is a complex organ, which consists of multiple components with highly diverse cell types. A detailed understanding of these cell types in health and disease is crucial for...
8.
Habener A, Grychtol R, Gaedcke S, DeLuca D, Dittrich A, Happle C, et al.
Eur Respir J . 2022 May; 60(5). PMID: 35595320
Background: Comprehensive studies investigated the role of T-cells in asthma which led to personalised treatment options targeting severe eosinophilic asthma. However, little is known about the contribution of B-cells to...
9.
Husing A, Wulfmeyer V, Gaedcke S, Fleig S, Rong S, DeLuca D, et al.
J Am Soc Nephrol . 2022 May; 33(8):1487-1500. PMID: 35537780
Background: The risk of cardiovascular events rises after AKI. Leukocytes promote atherosclerotic plaque growth and instability. We established a model of enhanced remote atherosclerosis after renal ischemia-reperfusion (IR) injury and...
10.
Maison N, Omony J, Illi S, Thiele D, Skevaki C, Dittrich A, et al.
Eur Respir J . 2022 Feb; 60(3). PMID: 35210326
Rationale: In adults, personalised asthma treatment targets patients with type 2 (T2)-high and eosinophilic asthma phenotypes. It is unclear whether such classification is achievable in children. Objectives: To define T2-high...