Suzanne J Randle
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Explore the profile of Suzanne J Randle including associated specialties, affiliations and a list of published articles.
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16
Citations
845
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Recent Articles
11.
Randle S, Nelson D, Patel S, Laman H
J Pathol
. 2015 Jun;
237(2):263-72.
PMID: 26095538
During the final stages of erythropoiesis, lineage-restricted progenitors mature over three to five cell divisions, culminating with withdrawal from the cell cycle and the loss of most organelles, including mitochondria...
12.
Nelson D, Randle S, Laman H
Open Biol
. 2013 Oct;
3(10):130131.
PMID: 24107298
F-box proteins (FBPs) are substrate-recruiting subunits of Skp1-cullin1-FBP (SCF)-type E3 ubiquitin ligases. To date, 69 FBPs have been identified in humans, but ubiquitinated substrates have only been identified for a...
13.
Burchell V, Nelson D, Sanchez-Martinez A, Delgado-Camprubi M, Ivatt R, Pogson J, et al.
Nat Neurosci
. 2013 Aug;
16(9):1257-65.
PMID: 23933751
Compelling evidence indicates that two autosomal recessive Parkinson's disease genes, PINK1 (PARK6) and Parkin (PARK2), cooperate to mediate the autophagic clearance of damaged mitochondria (mitophagy). Mutations in the F-box domain-containing...
14.
Lomonosov M, Meziane E, Ye H, Nelson D, Randle S, Laman H
PLoS One
. 2011 Jun;
6(6):e21165.
PMID: 21695055
Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts...
15.
Meziane E, Randle S, Nelson D, Lomonosov M, Laman H
J Cell Sci
. 2011 Jun;
124(Pt 13):2175-86.
PMID: 21652635
Fbxo7 is an unusual F-box protein because most of its interacting proteins are not substrates for ubiquitin-mediated degradation. Fbxo7 directly binds p27 and Cdk6, enhances the level of cyclin D-Cdk6...
16.
Adams S, Crook R, DeTure M, Randle S, Innes A, Yu X, et al.
Am J Pathol
. 2009 Sep;
175(4):1598-609.
PMID: 19717642
Here, we describe the generation and characterization of a novel tau transgenic mouse model (mTau) that overexpresses wild-type murine tau protein by twofold compared with endogenous levels. Transgenic tau expression...