Susumu Okamoto
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Explore the profile of Susumu Okamoto including associated specialties, affiliations and a list of published articles.
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84
Citations
2199
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Recent Articles
1.
Tokunaga K, Nakamura H, Toue S, Kato Y, Ida Y, Miyoshi S, et al.
Amino Acids
. 2023 Mar;
55(5):639-649.
PMID: 36930326
To prevent the progression of type 2 diabetes mellitus (T2DM), early detection and intervention are important. Several studies have already shown that the serum adiponectin level could be useful for...
2.
Hashimoto M, Watari S, Taguchi T, Ishikawa K, Kumamoto T, Okamoto S, et al.
Angew Chem Int Ed Engl
. 2022 Dec;
62(5):e202214400.
PMID: 36460615
A plethora of dimeric natural products exist with diverse chemical structures and biological activities. A major strategy for dimerization is aryl coupling catalyzed by cytochrome P450 or laccase. Actinorhodin (ACT)...
3.
Saito S, Keino H, Takasaki I, Abe S, Kohno H, Ichihara K, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142662
"Idiopathic" is the most common category of uveitis, representing cases in which a specific diagnosis has not been established despite work-up. Sarcoidosis is a systemic granulomatous disorder affecting multiple organs...
4.
Ishikawa K, Hashimoto M, Komatsu K, Taguchi T, Okamoto S, Ichinose K
Bioorg Med Chem Lett
. 2022 Apr;
66:128727.
PMID: 35413414
Actinorhodin (ACT) is a benzoisochromanequinone antibiotic produced by Streptomyces coelicolor A3(2), which has served as a favored model organism for comprehensive studies of antibiotic biosynthesis and its regulation. (S)-DNPA undergoes...
5.
Miyoshi J, Maeda T, Matsuoka K, Saito D, Miyoshi S, Matsuura M, et al.
Sci Rep
. 2021 Aug;
11(1):16440.
PMID: 34385588
Predicting the response of patients with ulcerative colitis (UC) to a biologic such as vedolizumab (VDZ) before administration is an unmet need for optimizing individual patient treatment. We hypothesized that...
6.
Ohno A, Miyoshi J, Kato A, Miyamoto N, Yatagai T, Hada Y, et al.
BMC Gastroenterol
. 2020 Jul;
20(1):232.
PMID: 32689949
Background: Gastric cancer after Helicobacter pylori (HP) eradication is a crucial clinical challenge today as HP eradication therapy is widely performed. Detecting gastric cancer after HP eradication tends to be...
7.
Wakita Y, Saiki A, Kaneda H, Segawa S, Tsuchiya Y, Kameya H, et al.
Sci Rep
. 2019 Dec;
9(1):19533.
PMID: 31862981
Complex interplay between the intestinal environment and the host has attracted considerable attention and has been well studied with respect to the gut microbiome and metabolome. Oxygen free radicals such...
8.
Hashimoto M, Taguchi T, Ishikawa K, Mori R, Hotta A, Watari S, et al.
Chembiochem
. 2019 Sep;
21(5):623-627.
PMID: 31532569
Flavin-dependent monooxygenases are ubiquitous in living systems and are classified into single- or two-component systems. Actinorhodin, produced by Streptomyces coelicolor, is a representative polycyclic polyketide that is hydroxylated through the...
9.
Miyoshi J, Matsuoka K, Yoshida A, Naganuma M, Hisamatsu T, Yajima T, et al.
Intest Res
. 2018 Oct;
16(4):635-640.
PMID: 30301334
Ulcerative colitis (UC) is one of the major clinical phenotypes of inflammatory bowel diseases. Although 5-aminosalicylic acid (5-ASA) is widely used for UC and its efficacy and safety have been...
10.
Funabashi S, Kataoka M, Inami T, Kikuchi T, Yanagisawa R, Ishiguro C, et al.
Circ J
. 2017 May;
81(7):1051-1053.
PMID: 28529263
Background: The present comparative study with healthy volunteers was conducted to investigate the depressive status and temperament in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Methods and results: The results...