Sushil K Mishra
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Explore the profile of Sushil K Mishra including associated specialties, affiliations and a list of published articles.
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27
Citations
353
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Recent Articles
1.
Berida T, Huang T, Weck S, Lutz M, McKee S, Kagerah N, et al.
bioRxiv
. 2025 Feb;
PMID: 39975250
Abstract Figure:
2.
Osada N, Mishra S, Nakano M, Tokoro Y, Nagae M, Doerksen R, et al.
iScience
. 2024 Dec;
27(11):111066.
PMID: 39668865
-Acetylglucosaminyltransferases-IVa (GnT-IVa or MGAT4A) and -IVb (MGAT4B) are glycosyltransferase isozymes synthesizing the β1,4-GlcNAc branch in -glycans, a glycan structure involved in diabetes. These enzymes uniquely have a non-catalytic lectin domain,...
3.
Endo H, Ono M, Takado Y, Matsuoka K, Takahashi M, Tagai K, et al.
Neuron
. 2024 Jun;
112(15):2540-2557.e8.
PMID: 38843838
Deposition of α-synuclein fibrils is implicated in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), while in vivo detection of α-synuclein pathologies in these illnesses has been challenging. Here,...
4.
Samanta P, Mishra S, Pomin V, Doerksen R
Molecules
. 2023 Sep;
28(17).
PMID: 37687244
The entry of SARS-CoV-2 into the host cell is mediated by its S-glycoprotein (SGP). Sulfated glycans bind to the SGP receptor-binding domain (RBD), which forms a ternary complex with its...
5.
Alkhodier R, Mishra S, Doerksen R, Colby D
J Chem Inf Model
. 2022 Dec;
63(1):375-386.
PMID: 36512328
Many glycosylated natural products display biological activity and are deglycosylated by the metabolic processes of the body. Although unnatural CF-glycosides have been proposed as nonhydrolyzable analogues, CF-derivatives of natural products...
6.
Haji S, Ito T, Guenther C, Nakano M, Shimizu T, Mori D, et al.
Elife
. 2022 Dec;
11.
PMID: 36479973
C-type lectin receptors (CLRs) elicit immune responses upon recognition of glycoconjugates present on pathogens and self-components. While Dectin-1 is the best-characterized CLR recognizing β-glucan on pathogens, the endogenous targets of...
7.
Kim S, Farrag M, Mishra S, Misra S, Sharp J, Doerksen R, et al.
Carbohydr Polym
. 2022 Nov;
301(Pt A):120316.
PMID: 36436858
Sulfated fucans (SFs) from echinoderms, such as sea cucumbers and sea urchins, present linear and regular sulfation patterns within defined oligosaccharide building blocks. The high molecular weights of these polymers...
8.
Shofolawe-Bakare O, De Mel J, Mishra S, Hossain M, Hamadani C, Pride M, et al.
Macromol Biosci
. 2022 Sep;
22(12):e2200281.
PMID: 36125638
Macrophages play a diverse, key role in many pathologies, including inflammatory diseases, cardiovascular diseases, and cancer. However, many therapeutic strategies targeting macrophages suffer from systemic off-target toxicity resulting in notoriously...
9.
Nagae M, Hirata T, Tateno H, Mishra S, Manabe N, Osada N, et al.
Commun Biol
. 2022 Jul;
5(1):695.
PMID: 35854001
N-Glycosylation is a common post-translational modification, and the number of GlcNAc branches in N-glycans impacts glycoprotein functions. N-Acetylglucosaminyltransferase-IVa (GnT-IVa, also designated as MGAT4A) forms a β1-4 GlcNAc branch on the...
10.
Khaje N, Eletsky A, Biehn S, Mobley C, Rogals M, Kim Y, et al.
Commun Biol
. 2022 May;
5(1):452.
PMID: 35551273
High resolution hydroxyl radical protein footprinting (HR-HRPF) is a mass spectrometry-based method that measures the solvent exposure of multiple amino acids in a single experiment, offering constraints for experimentally informed...