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Sushil K Jain

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Articles 105
Citations 3582
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Recent Articles
1.
Jain S, Margret J, Zachary Jr A, Lally M, Vanchiere J, Mhanna M, et al.
BMJ Nutr Prev Health . 2025 Jan; 7(2):e000856. PMID: 39882299
Background: Subjects with metabolic syndrome and obesity have higher levels of inflammation with depression of the vitamin D (VD) hydroxylase/metabolising genes () required to convert VD consumed in the diet...
2.
Margret J, Jain S
BMC Res Notes . 2024 Nov; 17(1):331. PMID: 39511686
Objective: B-type natriuretic peptide (BNP) is a neurohormone primarily secreted from cardiac ventricles in reaction to increased volume and pressure. The plasma level of BNP is used to measure the...
3.
Margret J, Jain S
Genes (Basel) . 2024 Sep; 15(9). PMID: 39336792
Blood-testis barrier (BTB) genes are crucial for the cellular mechanisms of spermatogenesis as they protect against detrimental cytotoxic agents, chemicals, and pathogens, thereby maintaining a sterile environment necessary for sperm...
4.
Margret J, Jain S
Biomolecules . 2024 Sep; 14(9). PMID: 39334937
Leydig cells are the primary source of testosterone or androgen production in male mammals. The blood-testis barrier (BTB) maintains structural integrity and safeguards germ cells from harmful substances by blocking...
5.
Stevens C, Weeks K, Jain S
Metab Syndr Relat Disord . 2024 Sep; 23(1):13-22. PMID: 39279596
Diabetes, a metabolic disease associated with an increased health care burden and mortality, is currently on the rise. Both upregulation of the mammalian target of rapamycin (mTOR) and decreased levels...
6.
Jain S, Margret J, Parsanathan R, Velusamy T
J Dairy Sci . 2024 Sep; 107(12):10221-10230. PMID: 39245163
Dairy products, such as whey proteins, have been effectively used to enhance the effectiveness of vitamin D (VD) fortification and optimize circulating 25-hydroxyvitamin D [25(OH)VD] levels. Whey protein is rich...
7.
Jain S, Margret J, Abrams S, Levine S, Bhusal K
Nutrients . 2024 Jul; 16(13). PMID: 38999752
Vitamin D receptors are expressed in many organs and tissues, which suggests that vitamin D (VD) affects physiological functions beyond its role in maintaining bone health. Deficiency or inadequacy of...
8.
Stevens C, Jain S
Int J Mol Sci . 2024 Jan; 25(2). PMID: 38279305
Vitamin D is known to have a positive effect on bone health. Despite the greater frequency of vitamin D deficiency in African Americans (AA), they have a higher bone mineral...
9.
Jain S, Margret J, Lally M
Free Radic Biol Med . 2023 Oct; 209(Pt 1):185-190. PMID: 37866755
The incidence of Alzheimer's disease (AD) is higher in people over the age of 65 and in African Americans (AA). Elevated acetylcholinesterase (AChE) activity has been considered a major player...
10.
Jain S, Stevens C, Margret J, Levine S
Antioxid Redox Signal . 2023 Sep; 40(10-12):663-678. PMID: 37756366
Excess oxidative stress and neuroinflammation are risk factors in the onset and progression of Alzheimer's disease (AD) and its association with amyloid-β plaque accumulation. Oxidative stress impairs acetylcholine (ACH) and...