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» Authors » Susanna Raitano

Susanna Raitano

Explore the profile of Susanna Raitano including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 175
Followers 0
Related Specialties
Cell Biology
General Medicine
Biology
Top 10 Co-Authors
Catherine M Verfaillie
Laura Ordovas
Kim Vanuytsel
Jolien Vanhove
Qing Cai
Nicky Helsen
Rangarajan Sambathkumar
Ludo Van Den Bosch
Wenting Guo
Pieter Berckmans
Published In
Stem Cell Reports
Front Physiol
J Vis Exp
Stem Cells Transl Med
J Nucl Med
Affiliations
Soon will be listed here.
Recent Articles
1.
ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson's Disease
Valadas J, Esposito G, Vandekerkhove D, Miskiewicz K, Deaulmerie L, Raitano S, et al.
Neuron . 2018 Jun; 98(6):1155-1169.e6. PMID: 29887339
Parkinson's disease patients report disturbed sleep patterns long before motor dysfunction. Here, in parkin and pink1 models, we identify circadian rhythm and sleep pattern defects and map these to specific...
2.
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Ordovas L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, et al.
Stem Cell Reports . 2018 Feb; 10(2):673. PMID: 29444475
No abstract available.
3.
Molecular Imaging of Human Embryonic Stem Cells Stably Expressing Human PET Reporter Genes After Zinc Finger Nuclease-Mediated Genome Editing
Wolfs E, Holvoet B, Ordovas L, Breuls N, Helsen N, Schonberger M, et al.
J Nucl Med . 2017 Jun; 58(10):1659-1665. PMID: 28596158
Molecular imaging is indispensable for determining the fate and persistence of engrafted stem cells. Standard strategies for transgene induction involve the use of viral vectors prone to silencing and insertional...
4.
Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus
Ordovas L, Boon R, Pistoni M, Chen Y, Sambathkumar R, Helsen N, et al.
J Vis Exp . 2016 Dec; (117). PMID: 27911376
Even with the revolution of gene-targeting technologies led by CRISPR-Cas9, genetic modification of human pluripotent stem cells (hPSCs) is still time consuming. Comparative studies that use recombinant lines with transgenes...
5.
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Ordovas L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, et al.
Stem Cell Reports . 2015 Oct; 5(5):918-931. PMID: 26455413
Tools for rapid and efficient transgenesis in "safe harbor" loci in an isogenic context remain important to exploit the possibilities of human pluripotent stem cells (hPSCs). We created hPSC master...
6.
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia
Raitano S, Ordovas L, De Muynck L, Guo W, Espuny-Camacho I, Geraerts M, et al.
Stem Cell Reports . 2015 Jan; 4(1):16-24. PMID: 25556567
To understand how haploinsufficiency of progranulin (PGRN) causes frontotemporal dementia (FTD), we created induced pluripotent stem cells (iPSCs) from patients carrying the GRN(IVS1+5G > C) mutation (FTD-iPSCs). FTD-iPSCs were fated...
7.
Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells
Cai Q, Bonfanti P, Sambathkumar R, Vanuytsel K, Vanhove J, Gysemans C, et al.
Stem Cells Transl Med . 2014 Feb; 3(4):489-99. PMID: 24493854
Pancreatic endocrine progenitors obtained from human embryonic stem cells (hESCs) represent a promising source to develop cell-based therapies for diabetes. Although endocrine pancreas progenitor cells have been isolated from mouse...
8.
Self-renewal of neural stem cells: implications for future therapies
Raitano S, Verfaillie C, Petryk A
Front Physiol . 2013 Mar; 4:49. PMID: 23513073
No abstract available.