Susan T C J M Arentsen-Peters
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Explore the profile of Susan T C J M Arentsen-Peters including associated specialties, affiliations and a list of published articles.
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17
Citations
345
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Recent Articles
1.
Verbeek T, Vrenken K, Arentsen-Peters S, Castro P, van de Ven M, van Tellingen O, et al.
Commun Biol
. 2024 Oct;
7(1):1257.
PMID: 39362994
KMT2A-rearranged acute lymphoblastic leukemia (ALL) is characterized by deregulation of the epigenome and shows susceptibility towards histone deacetylase (HDAC) inhibition. Most broad-spectrum HDAC inhibitors simultaneously target multiple human HDAC isoforms....
2.
Adriaanse F, Schneider P, Arentsen-Peters S, Fonseca A, Stutterheim J, Pieters R, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892207
Pediatric acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) exhibit favorable survival rates. However, for AML and ALL patients carrying gene translocations clinical outcome remains unsatisfactory. Key players in...
3.
Schneider P, Crump N, Arentsen-Peters S, Smith A, Hagelaar R, Adriaanse F, et al.
Exp Hematol Oncol
. 2023 Sep;
12(1):81.
PMID: 37740239
In KMT2A-rearranged acute lymphoblastic leukemia (ALL), an aggressive malignancy, oncogenic KMT2A-fusion proteins inappropriately recruit DOT1L to promote leukemogenesis, highlighting DOT1L as an attractive therapeutic target. Unfortunately, treatment with the first-in-class...
4.
Schneider P, Wander P, Arentsen-Peters S, Vrenken K, Rockx-Brouwer D, Adriaanse F, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686014
In acute lymphoblastic leukemia (ALL), chromosomal translocations involving the gene represent highly unfavorable prognostic factors and most commonly occur in patients less than 1 year of age. Rearrangements of the...
5.
Wander P, Arentsen-Peters S, Vrenken K, Pinhanos S, Koopmans B, Dolman M, et al.
Biomedicines
. 2022 Mar;
10(3).
PMID: 35327440
KMT2A-rearranged acute lymphoblastic leukemia (ALL) in infants (<1 year of age) represents an aggressive type of childhood leukemia characterized by a poor clinical outcome with a survival chance of <50%....
6.
Wander P, Arentsen-Peters S, Pinhanos S, Koopmans B, Dolman M, Ariese R, et al.
Transl Oncol
. 2021 Mar;
14(5):101048.
PMID: 33667892
Pediatric MLL-rearranged acute myeloid leukemia (AML) has a generally unfavorable outcome, primarily due to relapse and drug resistance. To overcome these difficulties, new therapeutic agents are urgently needed. Yet, implementing...
7.
Wander P, Cheung L, Pinhanos S, Jones L, Kerstjens M, Arentsen-Peters S, et al.
Leukemia
. 2020 Jun;
34(11):2898-2902.
PMID: 32488115
No abstract available.
8.
Cucchi D, Bachas C, van den Heuvel-Eibrink M, Arentsen-Peters S, Kwidama Z, Schuurhuis G, et al.
Cancers (Basel)
. 2020 May;
12(5).
PMID: 32429253
Novel treatment strategies are of paramount importance to improve clinical outcomes in pediatric AML. Since chemotherapy is likely to remain the cornerstone of curative treatment of AML, insights in the...
9.
Hollink I, van den Ouweland A, Beverloo H, Arentsen-Peters S, Zwaan C, Wagner A
J Med Genet
. 2017 Apr;
54(12):805-808.
PMID: 28432085
Background: Recently a novel syndromic form of overgrowth with intellectual disability and distinct facial features was identified caused by constitutional mutations in the epigenetic regulator DNA-methyltransferase 3A (), referred to...
10.
Houwing M, Koopman-Coenen E, Kersseboom R, Gooskens S, Appel I, Arentsen-Peters S, et al.
Int J Hematol
. 2015 Mar;
102(1):140-3.
PMID: 25728710
We report, for the first time, a non-syndromic infant with a reversible myeloproliferative disease that harbors a germline hereditary thrombopoietin (THPO) gene mutation, a condition that is known to induce...