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Susan Canny

Explore the profile of Susan Canny including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 273
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Recent Articles
1.
Dzanibe S, Wilk A, Canny S, Ranganath T, Alinde B, Rubelt F, et al.
Nat Commun . 2024 May; 15(1):4080. PMID: 38744812
While preventing vertical HIV transmission has been very successful, HIV-exposed uninfected infants (iHEU) experience an elevated risk to infections compared to HIV-unexposed and uninfected infants (iHUU). Here we present a...
2.
Koti A, Lanis A, Finlayson S, Canny S, Feldman E, Miller D, et al.
Am J Med Genet A . 2023 Aug; 191(12):2825-2830. PMID: 37548074
Subdural hemorrhages (SDHs) in children are most often observed in abusive head trauma (AHT), a distinct form of traumatic brain injury, but they may occur in other conditions as well,...
3.
Dzanibe S, Wilk A, Canny S, Ranganath T, Alinde B, Rubelt F, et al.
bioRxiv . 2023 Jun; PMID: 37292866
While preventing vertical HIV transmission has been very successful, the increasing number of HIV-exposed uninfected infants (iHEU) experience an elevated risk to infections compared to HIV-unexposed and uninfected infants (iHUU)....
4.
Canny S, Mellins E
F1000Res . 2017 Jul; 6:971. PMID: 28690841
Systemic juvenile idiopathic arthritis (sJIA) and its most significant complication, macrophage activation syndrome (MAS), have traditionally been treated with steroids and non-steroidal anti-inflammatory medications. However, the introduction of biologic medications...
5.
Goodwin M, Molleston J, Canny S, Abou El Hassan M, Willert E, Bremner R, et al.
J Virol . 2010 Aug; 84(22):12039-47. PMID: 20719946
Gammaherpesviruses are important oncogenic pathogens that transit between lytic and latent life cycles. Silencing the lytic gene expression program enables the establishment of latency and a lifelong chronic infection of...
6.
Goodwin M, Canny S, Steed A, Virgin H
J Virol . 2010 Jan; 84(7):3711-7. PMID: 20071569
Cytokines regulate viral gene expression with important consequences for viral replication and pathogenesis. Gamma interferon (IFN-gamma) is a key regulator of chronic murine gammaherpesvirus 68 (gammaHV68) infection and a potent...
7.
Egan M, Pearson M, Weiner S, Rajendran V, Rubin D, Glockner-Pagel J, et al.
Science . 2004 Apr; 304(5670):600-2. PMID: 15105504
Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). The most common mutation, DeltaF508, results in the production of a misfolded CFTR...
8.
Egan M, Glockner-Pagel J, Ambrose C, Cahill P, Pappoe L, Balamuth N, et al.
Nat Med . 2002 May; 8(5):485-92. PMID: 11984593
The most common mutation in cystic fibrosis, Delta F508, results in a cystic fibrosis transmembrane conductance regulator (CFTR) protein that is retained in the endoplasmic reticulum (ER). Retention is dependent...