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Susan A McDowell

Explore the profile of Susan A McDowell including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 252
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Recent Articles
1.
Nesson E, McDowell S
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36361794
An emerging therapeutic approach in the treatment of infectious disease is to augment the host response through repurposing of well-tolerated, non-antibiotic, host-directed therapeutics. Earlier retrospective studies identify a positive association...
2.
Evans M, McDowell S
Pharmaceutics . 2021 Dec; 13(12). PMID: 34959329
An emergent approach to bacterial infection is the use of host rather than bacterial-directed strategies. This approach has the potential to improve efficacy in especially challenging infection settings, including chronic,...
3.
Caffo L, Sneed B, Burcham C, Reed K, Hahn N, Bell S, et al.
Curr Pharm Biotechnol . 2019 Jul; 20(9):733-744. PMID: 31258074
Background: Recurrent pharyngotonsillitis due to Streptococcus pyogenes develops regardless of whether infecting strains are resistant or susceptible to first-line antimicrobials. Causation for recurrent infection is associated with the use of...
4.
Smelser L, Walker C, Burns E, Curry M, Black N, Metzler J, et al.
Curr Pharm Biotechnol . 2016 Mar; 17(10):886-93. PMID: 26927218
Statins are potent modulators of immune responses, resulting in their ability to enhance host survival from primary bacterial infections. Alterations in primary immune responses that may be beneficial for survival...
5.
Cordero D, Fullenkamp C, Pelly R, Reed K, Caffo L, Zahrt A, et al.
Curr Pharm Biotechnol . 2014 Sep; 15(8):727-37. PMID: 25213310
Staphylococcus aureus is a leading causative agent in sepsis, endocarditis, and pneumonia. An emerging concept is that prognosis worsens when the infecting S. aureus strain has the capacity to not...
6.
Smith A, Ellison A, Robinson A, Drake M, McDowell S, Mitchell J, et al.
J Food Prot . 2013 Apr; 76(4):674-9. PMID: 23575132
Quality control procedures during food processing may involve direct inoculation of food samples onto appropriate selective media for subsequent enumeration. However, sublethally injured bacteria often fail to grow, enabling them...
7.
Dewalt R, Petkovich D, Zahrt A, Bruns H, McDowell S
Biochem Biophys Res Commun . 2013 Feb; 432(4):695-700. PMID: 23410754
During severe sepsis, microvesicles that are positive for tissue factor (TF) are at increased levels within blood and in pulmonary lavage. These microvesicles potentially disperse TF, the major initiator of...
8.
Burns E, Smelser L, Then J, Stankiewicz T, Kushdilian M, McDowell S, et al.
Curr Pharm Biotechnol . 2012 Dec; 14(2):233-41. PMID: 23228241
Staphylococcus aureus is the most prevalent etiologic agent of sepsis. Statins, primarily prescribed for their cholesterol-lowering capabilities, may be beneficial for treating sepsis due to their anti-inflammatory properties. This study...
9.
McDowell S
Curr Pharm Biotechnol . 2012 Feb; 12(9):1440. PMID: 22309021
No abstract available.
10.
McDowell S
Curr Pharm Biotechnol . 2011 Mar; PMID: 21401522
No abstract available.