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Suresh Mahalingam

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Articles 113
Citations 3381
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Recent Articles
1.
Wang S, Mahalingam S, Merits A
Rev Med Virol . 2025 Mar; 35(2):e70030. PMID: 40064592
Alphaviruses are re-emerging vector-born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other...
2.
Liu X, Ng W, Zusinaite E, Freitas J, Taylor A, Yerragunta V, et al.
Nat Commun . 2024 Aug; 15(1):7225. PMID: 39187479
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) continues its significant health and economic impact globally. Despite the success of spike-protein vaccines in preventing severe disease, long-lasting protection against emerging...
3.
Omler A, Mutso M, Vaher M, Freitas J, Taylor A, David C, et al.
mBio . 2024 Jul; 15(8):e0099324. PMID: 38953633
Barmah Forest virus (BFV) is a mosquito-borne virus that causes arthralgia with accompanying rash, fever, and myalgia in humans. The virus is mainly found in Australia and has caused outbreaks...
4.
Rao S, Erku D, Mahalingam S, Taylor A
J Gen Virol . 2024 Feb; 105(2). PMID: 38421278
Chikungunya virus (CHIKV) causes chikungunya fever and has been responsible for major global epidemics of arthritic disease over the past two decades. Multiple CHIKV vaccine candidates are currently undergoing or...
5.
Ng W, Liu X, Ling Z, Santos C, Magalhaes L, Kueh A, et al.
Nat Commun . 2023 Oct; 14(1):6605. PMID: 37884534
Arthritogenic alphaviruses are positive-strand RNA viruses that cause debilitating musculoskeletal diseases affecting millions worldwide. A recent discovery identified the four-and-a-half-LIM domain protein 1 splice variant A (FHL1A) as a crucial...
6.
Rao S, Abeyratne E, Freitas J, Yang C, Tharmarajah K, Mostafavi H, et al.
Vaccine . 2023 May; 41(27):3976-3988. PMID: 37230889
Mosquito-transmitted chikungunya virus (CHIKV) is the causal pathogen of CHIKV disease and is responsible for global epidemics of arthritic disease. CHIKV infection can lead to severe chronic and debilitating arthralgia,...
7.
Roper R, Garzino-Demo A, Del Rio C, Brechot C, Gallo R, Hall W, et al.
Vaccine . 2023 Apr; 41(20):3171-3177. PMID: 37088603
The widespread outbreak of the monkeypox virus (MPXV) recognized in 2022 poses new challenges for public healthcare systems worldwide. With more than 86,000 people infected, there is concern that MPXV...
8.
Ng W, Ling Z, Kueh A, Herold M, West N, King N, et al.
mBio . 2023 Apr; 14(2):e0058823. PMID: 37036079
Arthritogenic alphaviruses such as Ross River virus (RRV) and Chikungunya virus (CHIKV) are responsible for large-scale epidemics that cause debilitating acute and chronic musculoskeletal diseases. MXRA8 was recently discovered as...
9.
Krishnan R, Stapledon C, Mostafavi H, Freitas J, Liu X, Mahalingam S, et al.
Front Immunol . 2023 Feb; 14:1030879. PMID: 36845136
Introduction: There is an unmet medical need for effective anti-inflammatory agents for the treatment of acute and post-acute lung inflammation caused by respiratory viruses. The semi-synthetic polysaccharide, Pentosan polysulfate sodium...
10.
Jeong G, Kwon H, Ng W, Liu X, Moon H, Yoon G, et al.
Nat Commun . 2022 Dec; 13(1):7675. PMID: 36509737
Although ocular manifestations are reported in patients with COVID-19, consensus on ocular tropism of SARS-CoV-2 is lacking. Here, we infect K18-hACE2 transgenic mice with SARS-CoV-2 using various routes. We observe...