Supriya Srinivasan
Overview
Explore the profile of Supriya Srinivasan including associated specialties, affiliations and a list of published articles.
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46
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1614
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Recent Articles
1.
Liu C, Khan A, Seban N, Littlejohn N, Shah A, Srinivasan S
Nat Commun
. 2024 Aug;
15(1):6869.
PMID: 39127676
In C. elegans mechanisms by which peripheral organs relay internal state information to the nervous system remain unknown, although strong evidence suggests that such signals do exist. Here we report...
2.
Srinivasan S, Mehra S, Bianchi A, Singh S, Dosch A, Amirian H, et al.
bioRxiv
. 2024 Jun;
PMID: 38903082
Background And Aims: induction of alcoholic chronic pancreatitis (ACP) causes significant acinar damage, increased fibroinflammatory response, and heightened activation of cyclic response element binding protein 1 (CREB) when compared with...
3.
4.
Liu C, Khan A, Seban N, Littlejohn N, Srinivasan S
bioRxiv
. 2023 Nov;
PMID: 37961386
In mechanisms by which peripheral organs relay internal state information to the nervous system remain unknown, although strong evidence suggests that such signals do exist. Here we report the discovery...
5.
Mehra S, Garrido V, Dosch A, Lamichhane P, Srinivasan S, Singh S, et al.
Cancer Res Commun
. 2023 Jul;
3(7):1224-1236.
PMID: 37448553
Significance: Immunotherapeutic agents are ineffective against pancreatic cancer, mainly due to the immunosuppressive tumor microenvironment and stromal desmoplasia. Our current study demonstrates the therapeutic utility of a novel gut microbial...
6.
Mehra S, Srinivasan S, Singh S, Zhou Z, Garrido V, De Castro Silva I, et al.
Am J Physiol Gastrointest Liver Physiol
. 2022 Sep;
323(4):G375-G386.
PMID: 36098401
Heavy alcohol consumption is the dominant risk factor for chronic pancreatitis (CP); however, treatment and prevention strategies for alcoholic chronic pancreatitis (ACP) remains limited. The present study demonstrates that ACP...
7.
Dosch A, Singh S, Dai X, Mehra S, De Castro Silva I, Bianchi A, et al.
Mol Cancer Ther
. 2021 Sep;
20(11):2280-2290.
PMID: 34518296
A hallmark of pancreatic ductal adenocarcinoma (PDAC) is the presence of a dense, desmoplastic stroma and the consequent altered interactions between cancer cells and their surrounding tumor microenvironment (TME) that...
8.
Willobee B, Gaidarski A, Dosch A, Castellanos J, Dai X, Mehra S, et al.
Mol Cancer Ther
. 2021 May;
20(7):1246-1256.
PMID: 34001634
Activating mutations, a defining feature of pancreatic ductal adenocarcinoma (PDAC), promote tumor growth in part through the activation of cyclin-dependent kinases (CDK) that induce cell-cycle progression. p16 (p16), encoded by...
9.
Srinivasan S
Elife
. 2021 Feb;
10.
PMID: 33635271
Making choices about food affects the metabolism and lifespan of fruit flies.
10.
Littlejohn N, Seban N, Liu C, Srinivasan S
Elife
. 2020 Oct;
9.
PMID: 33078707
The relationship between lipid metabolism and longevity remains unclear. Although fat oxidation is essential for weight loss, whether it remains beneficial when sustained for long periods, and the extent to...