Supriya G Prasanth
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Explore the profile of Supriya G Prasanth including associated specialties, affiliations and a list of published articles.
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57
Citations
3663
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Recent Articles
1.
Song Y, Shinn M, Bangru S, Wang Y, Sun Q, Hao Q, et al.
bioRxiv
. 2024 Nov;
PMID: 39554052
Hypoxia-induced alternative splicing (AS) regulates tumor progression and metastasis. Little is known about how such AS is controlled and whether higher-order genome and nuclear domain (ND) organizations dictate these processes....
2.
Singh D, Cong Z, Song Y, Liu M, Chaudhary R, Liu D, et al.
Mol Cell Biol
. 2024 Aug;
44(9):372-390.
PMID: 39133105
A significant number of the genetic alterations observed in cancer patients lie within nonprotein-coding segments of the genome, including regions coding for long noncoding RNAs (lncRNAs). LncRNAs display aberrant expression...
3.
Kurniawan F, Chakraborty A, Oishi H, Liu M, Arif M, Chen D, et al.
Mol Cell Biol
. 2024 Jun;
44(7):289-301.
PMID: 38867464
The human Origin Recognition Complex (ORC) is required not only for the initiation of DNA replication, but is also implicated in diverse cellular functions, including chromatin organization, centrosome biology, and...
4.
Ahmad H, Chetlangia N, Prasanth S
Biology (Basel)
. 2024 Mar;
13(3).
PMID: 38534422
In all eukaryotes, the initiation of DNA replication requires a stepwise assembly of factors onto the origins of DNA replication. This is pioneered by the Origin Recognition Complex, which recruits...
5.
Hao Q, Liu M, Daulatabad S, Gaffari S, Song Y, Srivastava R, et al.
Elife
. 2024 Jan;
13.
PMID: 38240312
Out of the several hundred copies of genes arranged in the nucleolar organizing regions (NOR) of the five human acrocentric chromosomes, ~50% remain transcriptionally inactive. NOR-associated sequences and epigenetic modifications...
6.
Lin Y, Liu D, Chakraborty A, Macias V, Brister E, Sonalkar J, et al.
Mol Cell Biol
. 2023 Apr;
43(4):143-156.
PMID: 37096556
The smallest subunit of the human Origin Recognition Complex, hOrc6, is required for DNA replication progression and plays an important role in mismatch repair (MMR) during S-phase. However, the molecular...
7.
Liu D, Sonalkar J, Prasanth S
Bioessays
. 2023 Feb;
45(4):e2200229.
PMID: 36811379
Error-free genome duplication and accurate cell division are critical for cell survival. In all three domains of life, bacteria, archaea, and eukaryotes, initiator proteins bind replication origins in an ATP-dependent...
8.
Kurniawan F, Prasanth S
Transcription
. 2022 Jul;
13(1-3):82-87.
PMID: 35904285
Transcription regulation is an important mechanism that controls pluripotency and differentiation. Transcription factors dictate cell fate decisions by functioning cooperatively with chromatin regulators. We have recently demonstrated that BEND3 (BANP,...
9.
Lin Y, Liu D, Chakraborty A, Kadyrova L, Song Y, Hao Q, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(22):e2121406119.
PMID: 35622890
In eukaryotes, the origin recognition complex (ORC) is required for the initiation of DNA replication. The smallest subunit of ORC, Orc6, is essential for prereplication complex (pre-RC) assembly and cell...
10.
Kurniawan F, Chetlangia N, Kamran M, Redon C, Pongor L, Sun Q, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(9).
PMID: 35217604
BEN domain-containing proteins are emerging rapidly as an important class of factors involved in modulating gene expression, yet the molecular basis of how they regulate chromatin function and transcription remains...