Sunita Patel-Hett
Overview
Explore the profile of Sunita Patel-Hett including associated specialties, affiliations and a list of published articles.
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13
Citations
860
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Recent Articles
1.
Patel-Hett S, Martin E, Mohammed B, Rakhe S, Sun P, Barrett J, et al.
Haemophilia
. 2019 Jul;
25(5):797-806.
PMID: 31336410
Introduction: Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of the extrinsic pathway that negatively regulates thrombin production during coagulation. Under haemophilic conditions, where the intrinsic coagulation pathway is...
2.
Suidan G, Singh P, Patel-Hett S, Chen Z, Volfson D, Yamamoto-Imoto H, et al.
Blood Adv
. 2018 Apr;
2(9):954-963.
PMID: 29700007
Alzheimer disease (AD) is a neurodegenerative disorder characterized by extracellular β-amyloid (Aβ) deposition. Although peripheral inflammation and cerebrovascular pathology are reported in AD, there is a lack of plasma biomarkers...
3.
Parng C, Singh P, Pittman D, Wright K, Leary B, Patel-Hett S, et al.
J Pharm Sci
. 2018 Mar;
107(7):1995-2004.
PMID: 29571739
Tissue factor pathway inhibitor (TFPI) exhibits multiple isoforms, which are known to present in multiple locations such as plasma, endothelium, and platelets. TFPI is an endogenous negative modulator of the...
4.
Zahr A, Alcaide P, Yang J, Jones A, Gregory M, Dela Paz N, et al.
Nat Commun
. 2016 Feb;
7:10363.
PMID: 26831939
Endomucin is a membrane-bound glycoprotein expressed luminally by endothelial cells that line postcapillary venules, a primary site of leukocyte recruitment during inflammation. Here we show that endomucin abrogation on quiescent...
5.
Jurak Begonja A, Gambaryan S, Schulze H, Patel-Hett S, Italiano Jr J, Hartwig J, et al.
Exp Hematol
. 2012 Sep;
41(1):91-101.e4.
PMID: 22981933
The cyclic nucleotides cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) regulate the activity of protein kinase A (PKA) and protein kinase G (PKG), respectively. This process helps maintain...
6.
Wandall H, Rumjantseva V, Sorensen A, Patel-Hett S, Josefsson E, Bennett E, et al.
Blood
. 2012 May;
120(3):626-35.
PMID: 22613794
Platelets are megakaryocyte subfragments that participate in hemostatic and host defense reactions and deliver pro- and antiangiogenic factors throughout the vascular system. Although they are anucleated cells that lack a...
7.
Patel-Hett S, DAmore P
Int J Dev Biol
. 2011 Jul;
55(4-5):353-63.
PMID: 21732275
The vasculature is a highly specialized organ that functions in a number of key physiological tasks including the transport of oxygen and nutrients to tissues. Formation of the vascular system...
8.
Patel-Hett S, Wang H, Begonja A, Thon J, Alden E, Wandersee N, et al.
Blood
. 2011 May;
118(6):1641-52.
PMID: 21566095
Megakaryocytes generate platelets by remodeling their cytoplasm first into proplatelets and then into preplatelets, which undergo fission to generate platelets. Although the functions of microtubules and actin during platelet biogenesis...
9.
Thon J, Montalvo A, Patel-Hett S, Devine M, Richardson J, Ehrlicher A, et al.
J Cell Biol
. 2010 Nov;
191(4):861-74.
PMID: 21079248
Megakaryocytes generate platelets by remodeling their cytoplasm into long proplatelet extensions, which serve as assembly lines for platelet production. Although the mechanics of proplatelet elongation have been studied, the terminal...
10.
Reems J, Wang W, Tsubata K, Abdurrahman N, Sundell B, Tijssen M, et al.
Exp Hematol
. 2008 Nov;
36(12):1714-27.
PMID: 19007685
High-density oligonucleotide microarrays were used to compare gene expression profiles from uncultured CD34+/CD38lo cells and culture-derived megakaryocytes (MKs). As previously published, three replicate microarray data sets from three different sources...