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Sunil K Narwal

Explore the profile of Sunil K Narwal including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Gomez-Gonzalez P, Gupta A, Drought L, Patel A, Okombo J, van der Watt M, et al.
Sci Adv . 2024 Dec; 10(49):eadq1383. PMID: 39642214
Cyclic nucleotide-dependent phosphodiesterases (PDEs) play essential roles in regulating the malaria parasite life cycle, suggesting that they may be promising antimalarial drug targets. PDE inhibitors are used safely to treat...
2.
Luth M, Godinez-Macias K, Chen D, Okombo J, Thathy V, Cheng X, et al.
Science . 2024 Nov; 386(6725):eadk9893. PMID: 39607932
Surveillance of drug resistance and the discovery of novel targets-key objectives in the fight against malaria-rely on identifying resistance-conferring mutations in parasites. Current approaches, while successful, require laborious experimentation or...
3.
Bennett J, Narwal S, Kabeche S, Abegg D, Thathy V, Hackett F, et al.
Cell Chem Biol . 2024 Aug; 31(9):1714-1728.e10. PMID: 39137783
Malaria, caused by Plasmodium falciparum, remains a significant health burden. One major barrier for developing antimalarial drugs is the ability of the parasite to rapidly generate resistance. We previously demonstrated...
4.
Bennett J, Narwal S, Kabeche S, Abegg D, Hackett F, Yeo T, et al.
bioRxiv . 2024 Jan; PMID: 38260474
Malaria, caused by remains a significant health burden. A barrier for developing anti-malarial drugs is the ability of the parasite to rapidly generate resistance. We demonstrated that Salinipostin A (SalA),...