Sundararajan Srinivasan
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Explore the profile of Sundararajan Srinivasan including associated specialties, affiliations and a list of published articles.
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16
Citations
124
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Recent Articles
1.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
2.
Coley K, Wang Q, Packer R, John C, Abner E, Reis K, et al.
Nicotine Tob Res
. 2025 Jan;
PMID: 39792440
Introduction: Varenicline is an α4β2 nicotinic acetylcholine receptor partial agonist with the highest therapeutic efficacy of any pharmacological smoking cessation aid and a 12-month cessation rate of 26%. Genetic variation...
3.
Zheng S, Henry A, Cannie D, Lee M, Miller D, McGurk K, et al.
Nat Genet
. 2024 Nov;
56(12):2646-2658.
PMID: 39572783
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular...
4.
Sterenborg R, Steinbrenner I, Li Y, Bujnis M, Naito T, Marouli E, et al.
Nat Commun
. 2024 Jan;
15(1):888.
PMID: 38291025
To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals...
5.
Beaumont R, Flatley C, Vaudel M, Wu X, Chen J, Moen G, et al.
Nat Genet
. 2023 Oct;
55(11):1807-1819.
PMID: 37798380
A well-functioning placenta is essential for fetal and maternal health throughout pregnancy. Using placental weight as a proxy for placental growth, we report genome-wide association analyses in the fetal (n ...
6.
Srinivasan S, Liju S, Sathish N, Siddiqui M, Anjana R, Pearson E, et al.
Diabetes Care
. 2023 Jun;
46(8):1515-1523.
PMID: 37308106
Objective: South Asians are diagnosed with type 2 diabetes (T2D) more than a decade earlier in life than seen in European populations. We hypothesized that studying the genomics of age...
7.
Bigossi M, Maroteau C, Dawed A, Taylor A, Srinivasan S, Melhem A, et al.
Eur Heart J Cardiovasc Pharmacother
. 2023 May;
9(6):536-545.
PMID: 37253618
Background And Aims: The efficacy of statin therapy is hindered by intolerance to the therapy, leading to discontinuation. Variants in SLCO1B1, which encodes the hepatic transporter OATB1B1, influence statin pharmacokinetics,...
8.
Mookan V, Machakalai R, Srinivasan S, Sigamani S, Kolandhasamy P, Gnanamoorthy P, et al.
Mar Pollut Bull
. 2023 May;
192:115008.
PMID: 37182243
The spatial concentration of heavy metals (Mn, Ni, Cu, Co, Zn, Cd, and Pb) was studied in coastal areas (n = 9) including water (n = 27) and sediment (n ...
9.
Soto-Pedre E, Newey P, Srinivasan S, Siddiqui M, Palmer C, Leese G
J Clin Endocrinol Metab
. 2022 Sep;
107(12):3302-3308.
PMID: 36102151
Context: A hypothesis-free genetic association analysis has not been reported for patients with primary hyperparathyroidism (PHPT). Objective: We aimed to investigate genetic associations with PHPT using both genome-wide association study...
10.
Schillemans T, Tragante V, Maitusong B, Gigante B, Cresci S, Laguzzi F, et al.
Front Physiol
. 2022 Jul;
13:909870.
PMID: 35812313
The knowledge of factors influencing disease progression in patients with established coronary heart disease (CHD) is still relatively limited. One potential pathway is related to peroxisome proliferator-activated receptor gamma coactivator-1...