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Sun Woo Sophie Kang

Explore the profile of Sun Woo Sophie Kang including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 226
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Recent Articles
1.
Kang S, Brown L, Miller C, Barrows K, Golino J, Cultraro C, et al.
bioRxiv . 2025 Jan; PMID: 39803529
Hepatic lipid accumulation, or Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), is a significant risk factor for liver cancer. Despite the rising incidence of MASLD, the underlying mechanisms of steatosis and...
2.
Kang S, Cunningham R, Miller C, Brown L, Cultraro C, Harned A, et al.
Nat Commun . 2024 Feb; 15(1):1799. PMID: 38418824
In the liver, mitochondria are exposed to different concentrations of nutrients due to their spatial positioning across the periportal and pericentral axis. How the mitochondria sense and integrate these signals...
3.
Pedro M, Lund K, Kang S, Chen T, Stuelten C, Porat-Shliom N, et al.
J Invest Dermatol . 2023 Dec; 144(6):1311-1321.e7. PMID: 38103827
Epithelial cells in the skin and other tissues rely on signals from their environment to maintain homeostasis and respond to injury, and GPCRs play a critical role in this communication....
4.
Pedro M, Lund K, Kang S, Chen T, Stuelten C, Porat-Shliom N, et al.
bioRxiv . 2023 Jul; PMID: 37398171
Epithelial cells in the skin and other tissues rely on signals from their environment to maintain homeostasis and respond to injury, and G protein-coupled receptors (GPCRs) play a critical role...
5.
Kang S, Cunningham R, Miller C, Brown L, Cultraro C, Harned A, et al.
bioRxiv . 2023 Jun; PMID: 37333328
In the liver, mitochondria are exposed to different concentrations of nutrients due to their spatial positioning across the periportal (PP) and pericentral (PC) axis. How these mitochondria sense and integrate...
6.
Cunningham R, Kang S, Porat-Shliom N
Am J Physiol Gastrointest Liver Physiol . 2023 Feb; 324(4):G245-G249. PMID: 36749570
Tumor heterogeneity is a hallmark of cancer but a challenging problem to dissect mechanistically. Less recognized is that cells within normal tissues are also remarkably diverse. Hepatocytes are a great...
7.
Gonzalez-Menendez P, Phadke I, Olive M, Joly A, Papoin J, Yan H, et al.
Blood . 2023 Feb; 141(20):2520-2536. PMID: 36735910
Metabolic programs contribute to hematopoietic stem and progenitor cell (HSPC) fate, but it is not known whether the metabolic regulation of protein synthesis controls HSPC differentiation. Here, we show that...
8.
Acevedo-Acevedo S, Stefkovich M, Kang S, Cunningham R, Cultraro C, Porat-Shliom N
Hepatol Commun . 2022 Mar; 6(8):1949-1961. PMID: 35357082
As important as the fasting response is for survival, an inability to shut it down once nutrients become available can lead to exacerbated disease and severe wasting. The liver is...
9.
Stefkovich M, Kang S, Porat-Shliom N
Curr Protoc . 2021 May; 1(5):e139. PMID: 34033261
The liver is central in maintaining glucose homeostasis. Indeed, impaired hepatic glucose uptake has been implicated in the development of hyperglycemia in type II diabetes (T2D) and non-alcoholic fatty liver...
10.
Kang S, Fu D
Crit Rev Eukaryot Gene Expr . 2020 May; 29(5):483-497. PMID: 32422004
Hepatocytes have well-defined polarized morphological structure. Establishment and maintenance of cellular polarity is crucial to the function and viability of hepatocytes. Many disorders, both genetic and acquired, and drugs can...