Sumin Lu
Overview
Explore the profile of Sumin Lu including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
367
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Recent Articles
1.
Jang W, Senarath K, Feinberg G, Lu S, Lambert N
Elife
. 2024 Nov;
13.
PMID: 39514269
Classical G-protein-coupled receptor (GPCR) signaling takes place in response to extracellular stimuli and involves receptors and heterotrimeric G proteins located at the plasma membrane. It has recently been established that...
2.
Feng W, Lu S, Wu Y, Li X, Han D, Zhao Y, et al.
Angew Chem Int Ed Engl
. 2024 Sep;
64(4):e202415815.
PMID: 39316428
Thermochromic fluorescent materials (TFMs) have attracted significant attention due to their unique fluorescent colorimetric response to temperature. However, existing TFMs still suffer from weak stimulus responsiveness, broad temperature response ranges,...
3.
Jang W, Senarath K, Feinberg G, Lu S, Lambert N
bioRxiv
. 2024 Mar;
PMID: 38496652
Classical G protein-coupled receptor (GPCR) signaling takes place in response to extracellular stimuli and involves receptors and heterotrimeric G proteins located at the plasma membrane. It has recently been established...
4.
Eisa N, Crowley V, Elahi A, Kommalapati V, Serwetnyk M, Llbiyi T, et al.
iScience
. 2023 Nov;
26(12):108308.
PMID: 38025772
Low response rates and immune-related adverse events limit the remarkable impact of cancer immunotherapy. To improve clinical outcomes, preclinical studies have shown that combining immunotherapies with N-terminal Hsp90 inhibitors resulted...
5.
Feng W, Wu Y, Chen D, Lu S, Zhao Y, Yan H
Chem Commun (Camb)
. 2023 Nov;
59(100):14823-14826.
PMID: 38009240
By leveraging natural saturated fatty acids with distinct melting points and swift reversible phase transitions, we correlated external thermal cues to monomer and excimer emissions of difluoroboron β-diketonate fluorophores. This...
6.
Jang W, Lu S, Xu X, Wu G, Lambert N
Nat Chem Biol
. 2023 Jan;
19(6):687-694.
PMID: 36646958
G protein-coupled receptors (GPCRs) selectively activate at least one of the four families of heterotrimeric G proteins, but the mechanism of coupling selectivity remains unclear. Structural studies emphasize structural complementarity...
7.
Saggu S, Chen Y, Cottingham C, Rehman H, Wang H, Zhang S, et al.
Mol Psychiatry
. 2022 Nov;
28(2):588-600.
PMID: 36357671
Posttraumatic stress disorder (PTSD) after the pandemic has emerged as a major neuropsychiatric component of post-acute COVID-19 syndrome, yet the current pharmacotherapy for PTSD is limited. The use of adrenergic...
8.
Zhang Q, Wang X, Li J, Lu S, Lu D
RSC Adv
. 2022 May;
9(33):19086-19094.
PMID: 35516882
Nanoslits composed of different layered nanomaterials attract great attention in the theoretical and experimental investigations of nanofluidic devices due to their geometric simplicity and unique surface properties. Although many efforts...
9.
Lu S, Jang W, Inoue A, Lambert N
PLoS One
. 2021 Apr;
16(4):e0247743.
PMID: 33886554
A large number of GPCRs are potentially valuable drug targets but remain understudied. Many of these lack well-validated activating ligands and are considered "orphan" receptors, and G protein coupling profiles...
10.
Liu Y, Cai B, Chong Y, Zhang H, Kemp C, Lu S, et al.
Cell Death Dis
. 2020 Oct;
11(10):884.
PMID: 33082322
Resistance to molecular therapies frequently occur due to genetic changes affecting the targeted pathway. In myeloid and lymphoid leukemias/lymphomas resulting from constitutive activation of FGFR1 kinases, resistance has been shown...