Sumadee De Silva
Overview
Explore the profile of Sumadee De Silva including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
48
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0
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Recent Articles
1.
Samarasinghe S, Hewage A, Siriwardana R, Tennekoon K, Niriella M, De Silva S, et al.
BMC Gastroenterol
. 2025 Mar;
25(1):151.
PMID: 40065199
Background: Single nucleotide polymorphisms (SNPs) in patatin-like phospholipase domain-containing protein 3 (PNPLA3), transmembrane 6 superfamily member 2 (TM6SF2) and membrane bound O-acyltransferase domain containing 7 (MBOAT7) genes were reported to...
2.
Arachchige N, Sirisena N, De Silva S, Senathilake K, Faizan M, Dissanayake V
Hum Genomics
. 2025 Feb;
19(1):12.
PMID: 39940038
Background: Next-generation sequencing (NGS)-based testing is a cost-effective method for identifying pathogenic germline genetic variations in cancer-predisposing genes in hereditary breast cancer. However, many of the variants detected through NGS...
3.
Vellan C, Islam T, De Silva S, Taib N, Prasanna G, Jayapalan J
Clin Biochem
. 2024 Jun;
129:110776.
PMID: 38823558
This review provides a contemporary examination of the evolving landscape of breast cancer (BC) diagnosis, focusing on the pivotal role of novel protein-based biomarkers. The overview begins by elucidating the...
4.
Samarasinghe N, Mahaliyanage D, De Silva S, Jasinge E, Punyasiri N, Dilanthi H
J Genet Eng Biotechnol
. 2022 Dec;
20(1):164.
PMID: 36512268
Background: Homocystinuria is an inherited, inborn error of homocysteine metabolism, which leads to the abnormal accumulation of homocysteine and its metabolites in blood and urine, resulting in various complications. Variants...
5.
De Silva S, Tennekoon K, Karunanayake E
Onco Targets Ther
. 2021 Oct;
14:5115-5129.
PMID: 34712050
Breast and colorectal cancers are two primary malignancies on which most of the research done worldwide investigates the potential genetic and environmental risk factors and thereby tries to develop therapeutic...
6.
Manoharan V, Karunanayake E, Tennekoon K, De Silva S, Imthikab A, De Silva K, et al.
BMC Cancer
. 2020 Feb;
20(1):72.
PMID: 32000721
Background: Breast cancer (BC) is known to be the most common malignancy in females whereas colorectal cancer (CRC) incidence also higher in both genders in Sri Lanka. TP53 is an...
7.
Manoharan V, Karunanayake E, Tennekoon K, De Silva S, De Silva K, Angunawela P, et al.
Mol Med Rep
. 2019 Mar;
19(4):2781-2791.
PMID: 30816478
Head and neck cancer (HNC) is the leading cancer in Sri Lankan males and second most common cancer among Sri Lankan females. This is the first study, to the best...
8.
De Silva S, Tennekoon K, Karunanayake E
Breast Cancer (Dove Med Press)
. 2019 Feb;
11:71-80.
PMID: 30718964
Cancer is a socioeconomical burden in any nation. Out of that, breast cancer is identified as the most common malignancy worldwide among women irrespective of age. As women are an...
9.
Sundralingam T, Tennekoon K, de Silva S, De Silva S, Hewage S, Ranasinghe R
Growth Horm IGF Res
. 2018 Nov;
42-43:94-101.
PMID: 30390533
Objective: Characterization of a deletion in the exon 1 and 5' regulatory region of the GHRHR gene in a proband with isolated growth hormone deficiency. Methods: Multiple ligation dependent probe...
10.
Sundralingam T, Tennekoon K, de Silva S, De Silva S, Hewage A
Growth Horm IGF Res
. 2017 Sep;
36:22-29.
PMID: 28910730
Objective: Genetic alterations in GH1 and GHRHR genes are known to cause isolated growth hormone deficiency (IGHD). Of these, GHRHR codon 72 mutation has been reported to be highly prevalent...