Sudhasri Mohanty
Overview
Explore the profile of Sudhasri Mohanty including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
408
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0
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Recent Articles
1.
Mohanty S, Kim J, Ganesan L, Phillips G, Robinson J, Anderson C
PLoS One
. 2013 Aug;
8(7):e70863.
PMID: 23923029
FcRn, a non-classical MHCI molecule, transports IgG from mother to young and regulates the rate of IgG degradation throughout life. Brambell proposed a mechanism that unified these two functions, saying...
2.
Ganesan L, Kim J, Wu Y, Mohanty S, Phillips G, Birmingham D, et al.
J Immunol
. 2012 Oct;
189(10):4981-8.
PMID: 23053513
It has long been known that the ITIM-bearing IgG Fc receptor (FcγRIIb, RIIb) is expressed on liver sinusoidal endothelial cells (LSEC) and that the liver is the major site of...
3.
Ganesan L, Mohanty S, Kim J, Clark K, Robinson J, Anderson C
PLoS Pathog
. 2011 Oct;
7(9):e1002281.
PMID: 21980295
The liver removes quickly the great bulk of virus circulating in blood, leaving only a small fraction to infect the host, in a manner characteristic of each virus. The scavenger...
4.
Mohanty S, Kim J, Ganesan L, Phillips G, Hua K, Jarjoura D, et al.
J Reprod Immunol
. 2009 Dec;
84(2):133-44.
PMID: 20015554
While generally accepted that FcRn of the human syncytiotrophoblast and the mouse yolk sac endoderm is the major IgG transporter, the finding of a different Fc receptor FcgammaRIIb (RIIb) in...
5.
Kim J, Mohanty S, Ganesan L, Hua K, Jarjoura D, Hayton W, et al.
J Immunol
. 2009 Feb;
182(5):2583-9.
PMID: 19234152
In adults, the nonclassical MHC class I molecule, FcRn, binds both IgG and albumin and rescues both from a degradative fate, endowing both proteins with high plasma concentrations. FcRn also...
6.
Kim J, Bronson C, Wani M, Oberyszyn T, Mohanty S, Chaudhury C, et al.
Exp Biol Med (Maywood)
. 2008 Apr;
233(5):603-9.
PMID: 18375831
FcRn, a nonclassical MHC-I protein bound to beta 2-microglobulin (beta 2m), diverts IgG and albumin from an intracellular degradative fate, prolonging the half-lives of both. While knockout mouse strains lacking...
7.
Chaudhury C, Kim J, Mehnaz S, Wani M, Oberyszyn T, Bronson C, et al.
J Nutr
. 2006 Nov;
136(12):2993-8.
PMID: 17116709
HFE, a major histocompatibility complex class I-related protein, is implicated in the iron overload disease, hereditary hemochromatosis. Whereas patients with hereditary hemochromatosis have low serum transferrin levels, little is known...
8.
Anderson C, Chaudhury C, Kim J, Bronson C, Wani M, Mohanty S
Trends Immunol
. 2006 May;
27(7):343-8.
PMID: 16731041
Recent evidence validates a forgotten 40-year-old hypothesis: the MHC-related Fc receptor for IgG (FcRn) protects albumin from intracellular catabolic degradation, as it does for IgG, accounting for the uniquely long...
9.
Wani M, Haynes L, Kim J, Bronson C, Chaudhury C, Mohanty S, et al.
Proc Natl Acad Sci U S A
. 2006 Mar;
103(13):5084-9.
PMID: 16549777
Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, suggesting a lack of the neonatal Fc receptor,...