Sudharshan Hariharan
Overview
Explore the profile of Sudharshan Hariharan including associated specialties, affiliations and a list of published articles.
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19
Citations
178
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Recent Articles
1.
Wang Y, Ji P, Hariharan S, Wang J, Okusanya O, Abuasal B, et al.
Clin Pharmacol Ther
. 2024 Jan;
115(3):440-451.
PMID: 38235832
Intravenous or subcutaneous routes of administration (ROAs) are common dosing routes for therapeutic proteins. Eleven therapeutic proteins with approval for one ROA have subsequently received approval for a second ROA....
2.
Fleming T, Garnett C, Conklin L, Corriol-Rohou S, Hariharan S, Hsu D, et al.
Ther Innov Regul Sci
. 2022 Sep;
57(1):109-120.
PMID: 36057747
Even with recent substantive improvements in health care in pediatric populations, considerable need remains for additional safe and effective interventions for the prevention and treatment of diseases in children. The...
3.
Merino M, Richardson N, Reaman G, Ande A, Zvada S, Liu C, et al.
Pediatr Blood Cancer
. 2020 Sep;
67(12):e28688.
PMID: 32896942
On May 16, 2019, the U.S. Food and Drug Administration (FDA) approved dalteparin sodium for the treatment of symptomatic venous thromboembolism (VTE) to reduce the risk of recurrence in pediatric...
4.
Senatore F, Jagadeesh G, Rose M, Pillai V, Hariharan S, Liu Q, et al.
Am J Cardiovasc Drugs
. 2019 Mar;
19(2):227.
PMID: 30820768
The author name that previously read.
5.
Senatore F, Jagadeesh G, Rose M, Pillai V, Hariharan S, Liu Q, et al.
Am J Cardiovasc Drugs
. 2018 Aug;
19(1):11-20.
PMID: 30144016
Distributive shock is a subset of shock marked by decreased systemic vascular resistance, organ hypoperfusion and altered oxygen extraction. Despite the use of intravenous fluids and either higher dose of...
6.
Hariharan S, Southworth M, Madabushi R
J Clin Pharmacol
. 2014 Jul;
54(8):884-8.
PMID: 25044100
No abstract available.
7.
Cholkar K, Hariharan S, Gunda S, Mitra A
AAPS PharmSciTech
. 2014 Jul;
15(6):1454-67.
PMID: 24980081
The purpose of this study was to develop a clear aqueous mixed nanomicellar formulation (MNF) of dexamethasone utilizing both D-α-tocopherol polyethylene glycol-1000 succinate (Vit E TPGS) and octoxynol-40 (Oc-40). In...
8.
Talluri R, Gaudana R, Hariharan S, Mitra A
Ophthalmol Eye Dis
. 2013 Jul;
1:21-31.
PMID: 23861607
Objective: To delineate the plasma pharmacokinetics and determine the corneal uptake of valine based stereoisomeric dipeptide prodrugs of acyclovir (ACV) in rats. Methods: Male Sprague-Dawley rats were used for the...
9.
Hariharan S, Madabushi R
J Clin Pharmacol
. 2011 Sep;
52(1 Suppl):119S-25S.
PMID: 21956605
The objective of this work was to derive a dosing regimen for dabigatran in patients with severe renal impairment by modeling and simulation. Data from a dedicated renal impairment study...
10.
Talluri R, Gaudana R, Hariharan S, Jain R, Mitra A
Clin Res Regul Aff
. 2011 Feb;
26(3):65-72.
PMID: 21278830
The objective of this work was to study the disposition kinetics of valine-valine-acyclovir (VVACV), a dipeptide ester prodrug of acyclovir following intravenous and oral administrations in rat. A validated LC-MS/MS...