Sudha Visvanathan
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Explore the profile of Sudha Visvanathan including associated specialties, affiliations and a list of published articles.
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61
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2815
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Recent Articles
1.
Farag A, Visvanathan S, Bachelez H, Morita A, Lebwohl M, Barker J, et al.
J Invest Dermatol
. 2024 Jul;
145(3):573-582.e8.
PMID: 39004117
EFFISAYIL 1 was a randomized, placebo-controlled study of spesolimab, an anti-IL-36 receptor antibody, in patients presenting with a generalized pustular psoriasis flare. Treatment with spesolimab led to more rapid pustular...
2.
Hernandez-Cordero A, Thomas L, Smail A, Lim Z, Saklatvala J, Chung R, et al.
J Allergy Clin Immunol
. 2024 May;
154(3):657-665.e9.
PMID: 38815935
Background: Palmoplantar pustulosis (PPP) is an inflammatory skin disorder that mostly affects smokers and manifests with painful pustular eruptions on the palms and soles. Although the disease can present with...
3.
Francis L, McCluskey D, Ganier C, Jiang T, Du-Harpur X, Gabriel J, et al.
Nat Commun
. 2024 Jan;
15(1):913.
PMID: 38291032
Biologic therapies targeting the IL-23/IL-17 axis have transformed the treatment of psoriasis. However, the early mechanisms of action of these drugs remain poorly understood. Here, we perform longitudinal single-cell RNA-sequencing...
4.
Garrido-Trigo A, Corraliza A, Veny M, Dotti I, Melon-Ardanaz E, Rill A, et al.
Nat Commun
. 2024 Jan;
15(1):857.
PMID: 38287036
No abstract available.
5.
Hawkes J, Visvanathan S, Krueger J
Front Immunol
. 2023 Dec;
14:1292941.
PMID: 38077370
Generalized pustular psoriasis (GPP) is a rare, chronic, inflammatory skin disorder characterized by recurrent flares associated with skin erythema, desquamation, and widespread superficial sterile pustules, which may be severe ("lakes...
6.
Garrido-Trigo A, Corraliza A, Veny M, Dotti I, Melon-Ardanaz E, Rill A, et al.
Nat Commun
. 2023 Jul;
14(1):4506.
PMID: 37495570
Ulcerative colitis and Crohn's disease are chronic inflammatory intestinal diseases with perplexing heterogeneity in disease manifestation and response to treatment. While the molecular basis for this heterogeneity remains uncharacterized, single-cell...
7.
Jayne D, Steffgen J, Romero-Diaz J, Bajema I, Boumpas D, Noppakun K, et al.
Arthritis Rheumatol
. 2023 May;
75(11):1983-1993.
PMID: 37192040
Objective: To characterize its dose-response relationship, BI 655064 (an anti-CD40 monoclonal antibody) was tested as an add-on to mycophenolate and glucocorticoids in patients with active lupus nephritis (LN). Methods: A...
8.
Niaouris A, Hernandez-Cordero A, Haddad S, Hassi N, Benzian-Olsson N, Diz C, et al.
J Invest Dermatol
. 2022 Sep;
143(3):504-508.e5.
PMID: 36174714
No abstract available.
9.
McCluskey D, Benzian-Olsson N, Mahil S, Hassi N, Wohnhaas C, Burden A, et al.
J Allergy Clin Immunol
. 2022 May;
150(4):882-893.
PMID: 35568077
Background: Palmoplantar pustulosis (PPP) is a severe inflammatory skin disorder characterized by eruptions of painful, neutrophil-filled pustules on the palms and soles. Although PPP has a profound effect on quality...
10.
Baum P, Visvanathan S, Garcet S, Roy J, Schmid R, Bossert S, et al.
J Allergy Clin Immunol
. 2021 Oct;
149(4):1402-1412.
PMID: 34678325
Background: The IL-36 pathway plays a key role in the pathogenesis of generalized pustular psoriasis (GPP). In a proof-of-concept clinical trial, treatment with spesolimab, an anti-IL-36 receptor antibody, resulted in...