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» Authors » Sudeshna Seal

Sudeshna Seal

Explore the profile of Sudeshna Seal including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 169
Followers 0
Related Specialties
Hematology
General Medicine
Oncology
Top 10 Co-Authors
T Eoin West
Sandra Schwarz
David M Hockenbery
Narisara Chantratita
Hans-Peter Kiem
Sarunporn Tandhavanant
Nicolle D Myers
H Joachim Deeg
Deirdre Ducken
Lara Lovelace-Macon
Published In
Blood
Cell Cycle
Infect Immun
Leuk Lymphoma
PLoS One
Affiliations
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Recent Articles
1.
Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to , a lung-tropic pathogen
Lovelace-Macon L, Baker S, Ducken D, Seal S, Rerolle G, Tomita D, et al.
Infect Immun . 2024 Apr; 92(5):e0006024. PMID: 38619302
Melioidosis is an emerging tropical infection caused by inhalation, inoculation, or ingestion of the flagellated, facultatively intracellular pathogen . The melioidosis case fatality rate is often high, and pneumonia, the...
2.
Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
Dickey A, Chantratita N, Tandhavanant S, Ducken D, Lovelace-Macon L, Seal S, et al.
PLoS Negl Trop Dis . 2019 May; 13(5):e0007354. PMID: 31067234
Background: Toll-like receptors (TLRs) are sentinel receptors of the innate immune system. TLR4 detects bacterial lipopolysaccharide (LPS) and TLR5 detects bacterial flagellin. A common human nonsense polymorphism, TLR5:c.1174C>T, results in...
3.
Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide
Chantratita N, Tandhavanant S, Myers N, Seal S, Arayawichanont A, Kliangsa-Ad A, et al.
PLoS One . 2013 Dec; 8(11):e81617. PMID: 24303060
B. pseudomallei is a gram-negative bacterium that causes the tropical infection melioidosis. In northeast Thailand, mortality from melioidosis approaches 40%. As exemplified by the lipopolysaccharide-Toll-like receptor 4 interaction, innate immune...
4.
microRNAs regulate human embryonic stem cell division
Qi J, Yu J, Shcherbata H, Mathieu J, Wang A, Seal S, et al.
Cell Cycle . 2009 Oct; 8(22):3729-41. PMID: 19823043
microRNAs (miRNAs) regulate numerous physiological processes such as cell division and differentiation in many tissue types including stem cells. To probe the role that miRNAs play in regulating processes relevant...
5.
Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals
Seal S, Hockenbery D, Spaulding E, Kiem H, Abbassi N, Deeg H
Exp Hematol . 2008 Oct; 36(12):1660-72. PMID: 18838202
Objective: Clonal marrow cells from patients with early myelodysplastic syndrome (MDS) undergo apoptosis in response to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL). Cells from advanced MDS are resistant to...
6.
Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines
Ying S, Seal S, Abbassi N, Hockenbery D, Kiem H, Li X, et al.
Leuk Lymphoma . 2007 May; 48(5):1003-14. PMID: 17487744
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces programmed cell death (apoptosis) preferentially in tumor cells. However, not all cancer cells are sensitive to TRAIL. We determined whether ligation of the...
7.
NF-kappaB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
Kerbauy D, Lesnikov V, Abbasi N, Seal S, Scott B, Deeg H
Blood . 2005 Aug; 106(12):3917-25. PMID: 16105982
Tumor necrosis factor (TNF)-alpha, a potent stimulus of nuclear factor-kappaB (NF-kappaB), is up-regulated in myelodysplastic syndrome (MDS). Here, we show that bone marrow mononuclear cells (BMMCs) and purified CD34+ cells...