Sudeshna Fisch
Overview
Explore the profile of Sudeshna Fisch including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
816
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0
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Recent Articles
1.
Hassan S, Rezaei Z, Luna E, Yilmaz-Aykut D, Lee M, Perea A, et al.
Small
. 2024 May;
20(32):e2312261.
PMID: 38733225
Myocardial infarction (MI) is a significant cardiovascular disease that restricts blood flow, resulting in massive cell death and leading to stiff and noncontractile fibrotic scar tissue formation. Recently, sustained oxygen...
2.
Kim H, Liu Y, Kim J, Kim Y, Klouda T, Fisch S, et al.
EMBO Rep
. 2024 Jan;
25(2):616-645.
PMID: 38243138
Vascular remodeling is the process of structural alteration and cell rearrangement of blood vessels in response to injury and is the cause of many of the world's most afflicted cardiovascular...
3.
Covington T, Pilz P, Mulhern R, Ngoy S, Loscalzo A, Liu J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Mar;
324(4):L550-L556.
PMID: 36880685
The stressed right ventricle (RV) is particularly susceptible to producing and accumulating reactive oxygen species, leading to extracellular matrix deposition and secretion of natriuretic peptides. The role of specific enzymes...
4.
Pilz P, Ward J, Chang W, Kiss A, Bateh E, Jha A, et al.
Circ Res
. 2022 Jun;
130(12):1888-1905.
PMID: 35679365
Heart failure (HF) describes a heterogenous complex spectrum of pathological conditions that results in structural and functional remodeling leading to subsequent impairment of cardiac function, including either systolic dysfunction, diastolic...
5.
Lin Y, Chen C, Shih J, Cheng B, Chang C, Lin M, et al.
J Am Heart Assoc
. 2021 Mar;
10(7):e019274.
PMID: 33749310
Background Mitral regurgitation (MR) is a major contributor for heart failure (HF) and atrial fibrillation. Despite the advancement of MR surgeries, an effective medical therapy to mitigate MR progression is...
6.
Chang W, Fisch S, Dangwal S, Chen M, Cheng S, Chen Z, et al.
Hypertens Res
. 2021 Feb;
44(7):803-812.
PMID: 33568793
Coronary flow velocity (CFV) is reduced in pathologic cardiac hypertrophy. This functional reduction is linked to adverse cardiac remodeling, hypertension and fibrosis, and angiotensin II (AngII) is a key molecular...
7.
MicroRNA-21 regulates right ventricular remodeling secondary to pulmonary arterial pressure overload
Chang W, Fisch S, Dangwal S, Mohebali J, Fiedler A, Chen M, et al.
J Mol Cell Cardiol
. 2021 Feb;
154:106-114.
PMID: 33548242
Right ventricular (RV) function is a critical determinant of survival in patients with pulmonary arterial hypertension (PAH). While miR-21 is known to associate with vascular remodeling in small animal models...
8.
Shih J, Lin Y, Fisch S, Cheng J, Kang N, Hong C, et al.
Diabetes
. 2020 Oct;
70(1):262-267.
PMID: 33115828
Dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, is approved for treatments of patients with diabetes. The DAPA-HF (Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure) trial disclosed DAPA's benefits...
9.
Fisch S, Bachner-Hinenzon N, Ertracht O, Guo L, Arad Y, Ben-Zvi D, et al.
J Am Heart Assoc
. 2020 May;
9(10):e014761.
PMID: 32378446
Background Marfan syndrome (MFS) is a genetically transmitted connective tissue disorder characterized by aortic root dilatation, dissection, and rupture. Molecularly, MFS pathological features have been shown to be driven by...
10.
Evangelisti A, Schimmel K, Joshi S, Shah K, Fisch S, Alexander K, et al.
J Vis Exp
. 2020 Apr;
(157).
PMID: 32225163
The zebrafish (Danio rerio) has become a very popular model organism in cardiovascular research, including human cardiac diseases, largely due to its embryonic transparency, genetic tractability, and amenity to rapid,...