Subin Xiong
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Explore the profile of Subin Xiong including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
105
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Recent Articles
1.
Wang J, Zhang S, Tan C, Wei Q, Xiong S
Curr Pharm Biotechnol
. 2023 Apr;
24(15):1972-1982.
PMID: 37066771
Introduction: Nintedanib (NDNB) is a novel triple-angiokinase inhibitor for the treatment of lung cancer. However, the oral bioavailability of NDNB is only 4.7% owing to the poor solubility and the...
2.
Tan C, Xiong S
Curr Drug Deliv
. 2022 Nov;
20(10):1547-1558.
PMID: 36415102
Background: Rivaroxaban is widely used for long-term prevention and maintenance therapy of thromboembolic disorders. The existing oral dosage forms of rivaroxaban lead to poor patient adherence because of repeated daily...
3.
Zhang S, Cui D, Xu J, Wang J, Wei Q, Xiong S
Int J Pharm
. 2020 Feb;
579:119120.
PMID: 32035254
The nano-particulate system for oral delivery faces a big challenge across the gastrointestinal bio-barriers. The aim was to explore the potential applications of bile acid transporter mediated the self-assembled hybrid...
4.
Yu J, Zhao F, Gao W, Yang X, Ju Y, Zhao L, et al.
ACS Nano
. 2019 Aug;
13(9):10002-10014.
PMID: 31433945
Reactive oxygen species (ROS) are crucial molecules in cancer therapy. Unfortunately, the therapeutic efficiency of ROS is unsatisfactory in clinic, primarily due to their rigorous production conditions. By taking advantage...
5.
Yi S, Wang J, Lu Y, Ma R, Gao Q, Liu S, et al.
AAPS PharmSciTech
. 2019 Jun;
20(6):219.
PMID: 31201583
Hydroxypropyl methylcellulose (HPMC) is a hydrophilic retarding-release polymer with the limited application in hot melt extrusion (HME) due to its high glass transition temperature (T 181-191°C) and melt viscosity. The...
6.
Chen J, Chen Y, Huang W, Wang H, Du Y, Xiong S
J Pharm Sci
. 2018 May;
107(9):2366-2376.
PMID: 29738699
The objectives of this study were to explore sodium dodecyl sulfate (SDS) and Soluplus on the crystallization inhibition and dissolution of felodipine (FLDP) extrudates by bottom-up and top-down approaches. FLDP...
7.
Chen Y, Huang W, Chen J, Wang H, Zhang S, Xiong S
J Pharm Sci
. 2018 Feb;
107(6):1615-1623.
PMID: 29454624
The aim was to explore the effects of nonpolar and polar protic solvents composed of dichloromethane (DCM) and ethanol (EtOH) on the properties of felodipine (FLDP) and Soluplus in solutions,...
8.
Wu H, Wang K, Wang H, Chen F, Huang W, Chen Y, et al.
Colloids Surf B Biointerfaces
. 2016 Oct;
149:97-104.
PMID: 27736727
The aim was to explore the potential application of novel self-assembled nanoparticles cross-linking thermosensitive hydrogels composed of polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (Soluplus) and tacrolimus (FK-506) for local therapy of rheumatoid...
9.
Zhang S, Wu J, Wang H, Wang T, Jin L, Shu D, et al.
AAPS PharmSciTech
. 2014 Feb;
15(3):620-9.
PMID: 24515270
The aim was to develop a liposomal oxymatrine conjugating D-alpha tocopheryl polyethylene glycol 1000 succinate (OMT-LIP) for enhanced therapeutics of hepatic fibrosis. OMT-LIP was prepared using the remote loading method....
10.
Wang T, Yin X, Lu Y, Shan W, Xiong S
Int J Nanomedicine
. 2012 Jun;
7:2325-37.
PMID: 22661889
Emodin is a multifunctional Chinese traditional medicine with poor water solubility. D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) is a pegylated vitamin E derivate. In this study, a novel liposomal-emodin-conjugating TPGS...