Struan C Murray
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Explore the profile of Struan C Murray including associated specialties, affiliations and a list of published articles.
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7
Citations
322
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Recent Articles
1.
Brown T, Howe F, Murray S, Wouters M, Lorenz P, Seward E, et al.
Mol Syst Biol
. 2018 Feb;
14(2):e8007.
PMID: 29440389
Antisense transcription is widespread in genomes. Despite large differences in gene size and architecture, we find that yeast and human genes share a unique, antisense transcription-associated chromatin signature. We asked...
2.
Howe F, Fischl H, Murray S, Mellor J
Bioessays
. 2016 Dec;
39(1):1-12.
PMID: 28004446
Tri-methylation of lysine 4 on histone H3 (H3K4me3) is a near-universal chromatin modification at the transcription start site of active genes in eukaryotes from yeast to man and its levels...
3.
Murray S, Mellor J
Bioarchitecture
. 2016 Jan;
6(1):12-21.
PMID: 26760777
Non-coding transcription across the antisense strands of genes is an abundant, pervasive process in eukaryotes from yeast to humans, however its biological function remains elusive. Here, we provide commentary on...
4.
Murray S, Haenni S, Howe F, Fischl H, Chocian K, Nair A, et al.
Nucleic Acids Res
. 2015 Jul;
43(16):7823-37.
PMID: 26130720
Genes from yeast to mammals are frequently subject to non-coding transcription of their antisense strand; however the genome-wide role for antisense transcription remains elusive. As transcription influences chromatin structure, we...
5.
Nguyen T, Fischl H, Howe F, Woloszczuk R, Serra Barros A, Xu Z, et al.
Elife
. 2014 Nov;
3:e03635.
PMID: 25407679
In yeast, many tandemly arranged genes show peak expression in different phases of the metabolic cycle (YMC) or in different carbon sources, indicative of regulation by a bi-modal switch, but...
6.
Howe F, Boubriak I, Sale M, Nair A, Clynes D, Grijzenhout A, et al.
Mol Cell
. 2014 Aug;
55(5):733-44.
PMID: 25127513
Gene transcription responds to stress and metabolic signals to optimize growth and survival. Histone H3 (H3) lysine 4 trimethylation (K4me3) facilitates state changes, but how levels are coordinated with the...
7.
Murray S, Serra Barros A, Brown D, Dudek P, Ayling J, Mellor J
Nucleic Acids Res
. 2011 Nov;
40(6):2432-44.
PMID: 22123739
The precise nature of antisense transcripts in eukaryotes such as Saccharomyces cerevisiae remains elusive. Here we show that the 3' regions of genes possess a promoter architecture, including a pre-initiation...