Steven S Giles
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Explore the profile of Steven S Giles including associated specialties, affiliations and a list of published articles.
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22
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1102
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Recent Articles
1.
Rojas M, Giles S, Little M, Baron R, Livingston I, Dagenais T, et al.
J Vis Exp
. 2021 Apr;
(170).
PMID: 33900300
To control community transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the 2020 global pandemic, most countries implemented strategies based on direct human testing, face covering, and surface...
2.
Kruzel E, Giles S, Hull C
Genetics
. 2012 Apr;
191(2):435-49.
PMID: 22466042
The fundamental mechanisms that control eukaryotic development include extensive regulation at the level of transcription. Gene regulatory networks, composed of transcription factors, their binding sites in DNA, and their target...
3.
Klassen J, Adams S, Bramhacharya S, Giles S, Goodwin L, Woyke T, et al.
J Bacteriol
. 2011 Nov;
193(24):6999-7000.
PMID: 22123757
Streptomyces sp. strain Wigar10 was isolated from a surface-sterilized garlic bulb (Allium sativum var. Purple Stripe). Its genome encodes several novel secondary metabolite biosynthetic gene clusters and provides a genetic...
4.
Stanton B, Giles S, Staudt M, Kruzel E, Hull C
PLoS Genet
. 2010 Mar;
6(2):e1000860.
PMID: 20195516
Cell type specification is a fundamental process that all cells must carry out to ensure appropriate behaviors in response to environmental stimuli. In fungi, cell identity is critical for defining...
5.
Stanton B, Giles S, Kruzel E, Warren C, Ansari A, Hull C
Mol Microbiol
. 2009 Jun;
72(6):1334-47.
PMID: 19486297
Homeodomain proteins function in fungi to specify cell types and control sexual development. In the meningoencephalitis-causing fungal pathogen Cryptococcus neoformans, sexual development leads to the production of spores (suspected infectious...
6.
Giles S, Dagenais T, Botts M, Keller N, Hull C
Infect Immun
. 2009 May;
77(8):3491-500.
PMID: 19451235
Cryptococcus neoformans was first described as a human fungal pathogen more than a century ago. One aspect of the C. neoformans infectious life cycle that has been the subject of...
7.
Botts M, Giles S, Gates M, Kozel T, Hull C
Eukaryot Cell
. 2009 Feb;
8(4):595-605.
PMID: 19181873
Spores are essential particles for the survival of many organisms, both prokaryotic and eukaryotic. Among the eukaryotes, fungi have developed spores with superior resistance and dispersal properties. For the human...
8.
Kent C, Ortiz-Bermudez P, Giles S, Hull C
Appl Environ Microbiol
. 2008 Sep;
74(20):6248-53.
PMID: 18776031
For over 3 decades, sexual development in the human fungal pathogen Cryptococcus neoformans and other fungi has been initiated by growing compatible mating partners on V8 juice medium. Although this...
9.
Zaas A, Liao G, Chien J, Weinberg C, Shore D, Giles S, et al.
PLoS Genet
. 2008 Jun;
4(6):e1000101.
PMID: 18566672
Invasive aspergillosis (IA) is a common and life-threatening infection in immunocompromised individuals. A number of environmental and epidemiologic risk factors for developing IA have been identified. However, genetic factors that...
10.
Dagenais T, Chung D, Giles S, Hull C, Andes D, Keller N
Infect Immun
. 2008 Apr;
76(7):3214-20.
PMID: 18443090
Oxygenated fatty acids, or oxylipins, play an essential role in physiological signaling and developmental processes in animals, plants, and fungi. Previous characterization of three Aspergillus fumigatus dioxygenases (PpoA, PpoB, and...