Steven M Santana
Overview
Explore the profile of Steven M Santana including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
365
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0
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Recent Articles
1.
Santana S, Antonyak M, Cerione R, Kirby B
Biomed Microdevices
. 2014 Oct;
16(6):869-77.
PMID: 25342569
Extracellular shed vesicles, including exosomes and microvesicles, are disseminated throughout the body and represent an important conduit of cell communication. Cancer-cell-derived microvesicles have potential as a cancer biomarker as they...
2.
Rhim A, Thege F, Santana S, Lannin T, Saha T, Tsai S, et al.
Gastroenterology
. 2013 Dec;
146(3):647-51.
PMID: 24333829
Hematogenous dissemination is thought to be a late event in cancer progression. We recently showed in a genetic model of pancreatic ductal adenocarcinoma that pancreas cells can be detected in...
3.
Galletti G, Sung M, Vahdat L, Shah M, Santana S, Altavilla G, et al.
Lab Chip
. 2013 Nov;
14(1):147-56.
PMID: 24202699
Circulating tumor cells (CTCs) have emerged as a reliable source of tumor cells, and their concentration has prognostic implications. CTC capture offers real-time access to cancer tissue without the need...
4.
Smith J, Lannin T, Syed Y, Santana S, Kirby B
Biomed Microdevices
. 2013 Oct;
16(1):143-51.
PMID: 24078270
The enrichment and isolation of rare cells from complex samples, such as circulating tumor cells (CTCs) from whole blood, is an important engineering problem with widespread clinical applications. One approach...
5.
Huang C, Santana S, Liu H, Bander N, Hawkins B, Kirby B
Electrophoresis
. 2013 Aug;
34(20-21):2970-9.
PMID: 23925921
The capture of circulating tumor cells (CTCs) from cancer patient blood enables early clinical assessment as well as genetic and pharmacological evaluation of cancer and metastasis. Although there have been...
6.
Smith J, Barbati A, Santana S, Gleghorn J, Kirby B
Electrophoresis
. 2012 Oct;
33(21):3133-42.
PMID: 23065634
The isolation and capture of rare cells is a problem uniquely suited to microfluidic devices, in which geometries on the cellular length scale can be engineered and a wide range...
7.
Kirby B, Jodari M, Loftus M, Gakhar G, Pratt E, Chanel-Vos C, et al.
PLoS One
. 2012 May;
7(4):e35976.
PMID: 22558290
Cancer metastasis accounts for the majority of cancer-related deaths owing to poor response to anticancer therapies. Molecular understanding of metastasis-associated drug resistance remains elusive due to the scarcity of available...
8.
Santana S, Liu H, Bander N, Gleghorn J, Kirby B
Biomed Microdevices
. 2011 Dec;
14(2):401-7.
PMID: 22143878
Patients suffering from cancer can shed tumor cells into the bloodstream, leading to one of the most important mechanisms of metastasis. As such, the capture of these cells is of...