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Steven J Nieto

Explore the profile of Steven J Nieto including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 427
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Recent Articles
1.
Kirsch D, Grodin E, Nieto S, Kady A, Ray L
Neuropsychopharmacology . 2024 May; 49(11):1719-1728. PMID: 38740901
Early life stress (ELS) increases risk for psychiatric illness, including alcohol use disorder (AUD). Researchers have hypothesized that individuals with and without a history of ELS who have the same...
2.
Nieto S, Du H, Meredith L, Donato S, Magill M, Ray L
Psychopharmacology (Berl) . 2024 Apr; 241(8):1679-1689. PMID: 38613685
Rationale: The alcohol cue exposure paradigm is a common method for evaluating new treatments for alcohol use disorder (AUD); however, it is unclear if medication-related reductions in cue-induced craving in...
3.
Nieto S, Grodin E, Ray L
Behav Brain Res . 2024 Mar; 464:114926. PMID: 38431152
The Addictions Neuroclinical Assessment (ANA) is a recently-developed framework offering a more holistic understanding of three neurofunctional and behavioral domains that reflect the neurobiological dysfunction seen in alcohol use disorder...
4.
Ray L, Baskerville W, Nieto S, Grodin E, Enders C, Kady A, et al.
Psychopharmacology (Berl) . 2023 Nov; 241(3):543-553. PMID: 38012333
Rationale: Screening novel medications for alcohol use disorder (AUD) requires models that are both efficient and ecologically-valid. Ideally, such models would be associated with the outcomes of a given medication...
5.
Ray L, Nieto S, Meredith L, Burnette E, Donato S, Magill M, et al.
Psychopharmacology (Berl) . 2023 Jul; 240(9):1921-1930. PMID: 37452887
Rationale: Alcohol administration and cue-reactivity paradigms are frequently used to screen for the initial efficacy of medications for alcohol use disorder (AUD). While medication effects on the primary outcomes for...
6.
Meredith L, Burnette E, Nieto S, Du H, Donato S, Grodin E, et al.
Alcohol Clin Exp Res (Hoboken) . 2023 Jul; 47(9):1629-1645. PMID: 37423771
Alcohol cue exposure is a widely used experimental paradigm for screening pharmacotherapies for alcohol use disorder (AUD). Medication-related reductions in cue-reactivity signal early efficacy and inform medications development. Yet, across...
7.
Nieto S, Kosten T
Alcohol Clin Exp Res (Hoboken) . 2023 Jun; 47(8):1494-1504. PMID: 37353981
Background: The heritability of alcohol use disorder is close to 50%, yet common genetic variants account for less than 5% of risk. The missing heritability may reflect environmental exposure in...
8.
Nieto S, Enders C, Witkiewitz K, OMalley S, Ray L
Alcohol Clin Exp Res . 2022 Dec; 46(12):2258-2266. PMID: 36515648
Background: The U.S. Food and Drug Administration identifies abstinence and the absence of heavy drinking days as outcomes for pharmacotherapy trials for alcohol use disorder (AUD). However, many individuals with...
9.
Ray L, Nieto S, Grodin E
Ann N Y Acad Sci . 2022 Nov; 1519(1):118-128. PMID: 36385614
Alcohol and substance use disorders are heterogeneous conditions with limited effective treatment options. While there have been prior attempts to classify addiction subtypes, they have not been translated into clinical...
10.
Nieto S, Harding M, Nielsen D, Kosten T
Alcohol Clin Exp Res . 2022 Oct; 46(12):2191-2202. PMID: 36281832
Background: Endophenotypes for alcohol use disorder are well known and may reflect paternal exposure effects passed down to offspring via epigenetic mechanisms. Previously, we showed that paternal alcohol exposure prior...