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Steven E Bosinger

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Articles 136
Citations 5228
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Recent Articles
1.
Gabernet G, Maciuch J, Gygi J, Moore J, Hoch A, Syphurs C, et al.
bioRxiv . 2025 Feb; PMID: 39990442
Following SARS-CoV-2 infection, ~10-35% of COVID-19 patients experience long COVID (LC), in which often debilitating symptoms persist for at least three months. Elucidating the biologic underpinnings of LC could identify...
2.
Edwards C, Karunakaran K, Garcia E, Beutler N, Gagne M, Golden N, et al.
PLoS Pathog . 2025 Jan; 21(1):e1012456. PMID: 39847599
The continued evolution of SARS-CoV-2 variants capable of subverting vaccine and infection-induced immunity suggests the advantage of a broadly protective vaccine against betacoronaviruses (β-CoVs). Recent studies have isolated monoclonal antibodies...
3.
Peres A, Upadhyay A, Klein V, Klein V, Saha S, Rodriguez O, et al.
bioRxiv . 2025 Jan; PMID: 39829807
Rhesus macaques (RMs) are a vital model for studying human disease and invaluable to pre-clinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust...
4.
Bekhbat M, Block A, Dickinson S, Tharpd G, Tharp G, Bosinger S, et al.
Brain Behav Immun . 2025 Jan; 125:308-318. PMID: 39826580
Inflammatory stimuli administered to humans and laboratory animals affect mesolimbic and nigrostriatal dopaminergic pathways in association with impaired motivation and motor activity. Alterations in dopaminergic corticostriatal reward and motor circuits...
5.
Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, Rouphael N, et al.
Nat Commun . 2025 Jan; 16(1):586. PMID: 39794319
Coronavirus disease 2019 (COVID-19) poses significant risks for solid organ transplant recipients, who have atypical but poorly characterized immune responses to infection. We aim to understand the host immunologic and...
6.
Madden P, Marina-Zarate E, Rodrigues K, Steichen J, Shil M, Ni K, et al.
bioRxiv . 2024 Dec; PMID: 39651117
Rare B cells can have special pathogen-recognition features giving them the potential to make outsized contributions to protective immunity. However, rare naive B cells infrequently participate in immune responses. We...
7.
Williams D, Gautam S, Creech C, Jimenez N, Anderson E, Bosinger S, et al.
J Infect Dis . 2024 Oct; 231(2):e277-e289. PMID: 39397536
Background: Challenges remain in discerning microbiologic etiology and disease severity in childhood pneumonia. Defining host transcriptomic profiles during illness may facilitate improved diagnostic and prognostic approaches. Methods: Using whole blood...
8.
Moore K, Foster S, Kar M, Floyd K, Elrod E, Williams M, et al.
bioRxiv . 2024 Aug; PMID: 39211190
Waning immunity and the emergence of immune evasive SARS-CoV-2 variants jeopardize vaccine efficacy leading to breakthrough infections. We have previously shown that innate immune cells play a critical role in...
9.
Edwards C, Karunakaran K, Garcia E, Beutler N, Gagne M, Golden N, et al.
bioRxiv . 2024 Aug; PMID: 39109178
The continued evolution of SARS-CoV-2 variants capable of subverting vaccine and infection-induced immunity suggests the advantage of a broadly protective vaccine against betacoronaviruses (β-CoVs). Recent studies have isolated monoclonal antibodies...
10.
Strongin Z, Raymond Marchand L, Deleage C, Pampena M, Cardenas M, Beusch C, et al.
Nat Immunol . 2024 Jun; 25(7):1245-1256. PMID: 38886592
Human immunodeficiency virus (HIV) cure efforts are increasingly focused on harnessing CD8 T cell functions, which requires a deeper understanding of CD8 T cells promoting HIV control. Here we identifiy...