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Steven Dow

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Articles 98
Citations 1578
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Recent Articles
1.
Ammons D, Harris R, Chow L, Dow S
Cancer Immunol Immunother . 2025 Feb; 74(3):105. PMID: 39932553
Immune cells play key roles in host responses to malignant tumors. The selective pressure that immune cells elicit on tumors promotes immune escape, while tumor-associated modulation of immune cells creates...
2.
Chow L, Kawahisa-Piquini G, Bass L, Hendrickson D, Patel A, Rockow M, et al.
Ann Transl Med . 2025 Jan; 12(6):112. PMID: 39817240
Background: Osteoarthritis (OA) is increasingly thought to be a multifactorial disease in which sustained gut inflammation serves as a continued source of inflammatory mediators driving degenerative processes at distant sites...
3.
Boss M, Burdekin B, Harrison L, Rivera M, Harris A, Rout E, et al.
J Vis Exp . 2025 Jan; 214. PMID: 39803946
Evaluating the local immune microenvironment of the canine nasal cavity can be important for investigating normal tissue health and disease conditions, particularly those associated with local inflammation. We have optimized...
4.
Seabaugh K, Rao S, Koenig J, Pezzanite L, Dow S, Koch T, et al.
Animals (Basel) . 2024 Dec; 14(23). PMID: 39682372
Synovitis is present before and during osteoarthritis in horses and can result in performance-limiting lameness. Twenty-four horses with lameness localized to the metacarpo-/metatarsophalangeal joint or a single joint of the...
5.
Ammons D, Chow L, Goodrich L, Bass L, Larson B, Williams Z, et al.
Ann Transl Med . 2024 Nov; 12(5):88. PMID: 39507442
Background: Osteoarthritis (OA) is a major source of pain and disability worldwide. Understanding of disease progression is evolving, but OA is increasingly thought to be a multifactorial disease in which...
6.
Darragh L, Gadwa J, Pham T, Van Court B, Neupert B, Olimpo N, et al.
Nat Commun . 2024 Oct; 15(1):8781. PMID: 39389942
No abstract available.
7.
Wang Z, Chow L, Das S, Impastato R, Manchester A, Dow S
Front Vet Sci . 2024 Aug; 11:1385471. PMID: 39188898
Chronic rhinitis (CR) is a frustrating clinical syndrome in dogs and our understanding of the disease pathogenesis in is limited. Increasingly, host-microbe interactions are considered key drives of clinical disease...
8.
Cerna P, Dow S, Wheat W, Chow L, Hawley J, Lappin M
Pathogens . 2024 Jul; 13(7). PMID: 39057828
Background: Effective immunotherapeutic agents for use in cats are needed to aid in the management of intractable viral diseases, including feline infectious peritonitis (FIP) infection. The objectives of this study...
9.
Manchester A, Ammons D, Lappin M, Dow S
Front Immunol . 2024 Jun; 15:1397590. PMID: 38933260
Chronic inflammatory enteropathy (CIE) is a common condition in dogs causing recurrent or persistent gastrointestinal clinical signs. Pathogenesis is thought to involve intestinal mucosal inflammatory infiltrates, but histopathological evaluation of...
10.
Williams Z, Chow L, Dow S, Pezzanite L
Front Vet Sci . 2024 May; 11():1369153. PMID: 38812556
Cellular senescence, a condition where cells undergo arrest and can assume an inflammatory phenotype, has been associated with initiation and perpetuation of inflammation driving multiple disease processes in rodent models...