Steven A Siegelbaum
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Explore the profile of Steven A Siegelbaum including associated specialties, affiliations and a list of published articles.
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77
Citations
5136
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Recent Articles
1.
Kassraian P, Bigler S, Gilly Suarez D, Shrotri N, Barnett A, Lee H, et al.
Nat Neurosci
. 2024 Oct;
27(11):2193-2206.
PMID: 39406949
The dorsal cornu ammonis 2 (dCA2) region of the hippocampus enables the discrimination of novel from familiar conspecifics. However, the neural bases for more complex social-spatial episodic memories are unknown....
2.
Buss E, Lofaro O, Barnett A, Leroy F, Santoro B, Siegelbaum S, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2319246121.
PMID: 39378096
Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels generate the cationic I current in neurons and regulate the excitability of neuronal networks. The function of HCN channels depends, in part, on their subcellular...
3.
Buss E, Jiang Y, Santoro B, Brann D, Nicholson D, Siegelbaum S, et al.
Neuroscience
. 2024 Jun;
PMID: 38878815
Entorhinal cortex (EC) LIII and LII glutamatergic neurons make monosynaptic connections onto distal apical dendrites of hippocampal CA1 and CA2 pyramidal neurons (PNs), respectively, through perforant path (PP) projections. We...
4.
Villegas A, Siegelbaum S
bioRxiv
. 2024 May;
PMID: 38746353
The dorsal CA2 subregion (dCA2) of the hippocampus exerts a critical role in social novelty recognition (SNR) memory and in the promotion of social aggression. Whether the social aggression and...
5.
Castillo P, Desarmenien M, Siegelbaum S
Neuron
. 2024 May;
112(9):1387-1389.
PMID: 38697022
No abstract available.
6.
Boyle L, Posani L, Irfan S, Siegelbaum S, Fusi S
Neuron
. 2024 Feb;
112(8):1358-1371.e9.
PMID: 38382521
Social memory consists of two processes: the detection of familiar compared with novel conspecifics and the detailed recollection of past social episodes. We investigated the neural bases for these processes...
7.
Whitebirch A, Santoro B, Barnett A, Lisgaras C, Scharfman H, Siegelbaum S
J Neurosci
. 2023 Aug;
43(41):6930-6949.
PMID: 37643861
A significant proportion of temporal lobe epilepsy (TLE) patients experience drug-resistant seizures associated with mesial temporal sclerosis, in which there is extensive cell loss in the hippocampal CA1 and CA3...
8.
Kassraian P, Bigler S, Gilly D, Shrotri N, Siegelbaum S
bioRxiv
. 2023 Jul;
PMID: 37461518
The ability to distinguish a threatening from non-threatening conspecific based on past experience is critical for adaptive social behaviors. Although recent progress has been made in identifying the neural circuits...
9.
Social odor discrimination and its enhancement by associative learning in the hippocampal CA2 region
Hassan S, Bigler S, Siegelbaum S
Neuron
. 2023 May;
111(14):2232-2246.e5.
PMID: 37192623
Although the hippocampus is crucial for social memory, how social sensory information is combined with contextual information to form episodic social memories remains unknown. Here, we investigated the mechanisms for...
10.
Lisgaras C, Oliva A, Mckenzie S, LaFrancois J, Siegelbaum S, Scharman H
bioRxiv
. 2023 Jan;
PMID: 36711983
Highlights: Real-time CA2 silencing at the onset of seizures reduces seizure durationWhen CA2 silencing reduces seizure activity in hippocampus it also reduces cortical seizure activity and convulsive manifestations of seizuresInterictal...