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Steven A Julious

Explore the profile of Steven A Julious including associated specialties, affiliations and a list of published articles. Areas
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Articles 81
Citations 2814
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Recent Articles
1.
Zhang Q, Dimairo M, Julious S, Lewis J, Yu Z
BMC Med Res Methodol . 2024 Sep; 24(1):216. PMID: 39333920
Background: An adaptive design allows modifying the design based on accumulated data while maintaining trial validity and integrity. The final sample size may be unknown when designing an adaptive trial....
2.
Salsbury J, Oakley J, Julious S, Hampson L
Stat Med . 2024 Jun; 43(19):3595-3612. PMID: 38881219
An assurance calculation is a Bayesian alternative to a power calculation. One may be performed to aid the planning of a clinical trial, specifically setting the sample size or to...
3.
Alyami R, Simpson R, Oliver P, Julious S
Lancet . 2023 Nov; 402 Suppl 1:S22. PMID: 37997062
Background: Asthma exacerbations peak in school-aged children after the return to school in September. Previous studies have shown a decline in collections of asthma prescriptions during August. The PLEASANT trial...
4.
Totton N, Julious S, Coates E, Hughes D, Cook J, Biggs K, et al.
Health Technol Assess . 2023 Nov; 27(20):1-58. PMID: 37982521
Background: Randomised controlled trials are designed to assess the superiority, equivalence or non-inferiority of a new health technology, but which trial design should be used is not always obvious in...
5.
Junqueira D, Zorzela L, Golder S, Loke Y, Gagnier J, Julious S, et al.
J Clin Epidemiol . 2023 Apr; 158:149-165. PMID: 37100738
Randomized controlled trials remain the reference standard for healthcare research on effects of interventions, and the need to report both benefits and harms is essential. The Consolidated Standards of Reporting...
6.
Junqueira D, Zorzela L, Golder S, Loke Y, Gagnier J, Julious S, et al.
BMJ . 2023 Apr; 381:e073725. PMID: 37094878
No abstract available.
7.
Edwards J, Walters S, Julious S
Trials . 2023 Mar; 24(1):215. PMID: 36949524
Background: Adaptive clinical trials may use conditional power (CP) to make decisions at interim analyses, requiring assumptions about the treatment effect for remaining patients. It is critical that these assumptions...
8.
Iflaifel M, Sprange K, Bell J, Cook A, Gamble C, Julious S, et al.
Trials . 2023 Feb; 24(1):71. PMID: 36721215
Background: Existing guidelines recommend statisticians remain blinded to treatment allocation prior to the final analysis and that any interim analyses should be conducted by a separate team from the one...
9.
Alyami R, Simpson R, Oliver P, Julious S
Trials . 2022 Nov; 23(1):947. PMID: 36397087
Background: There is a marked increase in unscheduled care visits in school-aged children with asthma after returning to school in September. This is potentially associated with children not taking their...
10.
Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, et al.
Health Technol Assess . 2022 Oct; 26(39):1-100. PMID: 36259684
Background: The mainstay of treatment for diabetic peripheral neuropathic pain is pharmacotherapy, but the current National Institute for Health and Care Excellence guideline is not based on robust evidence, as...